The effect of pre-endoscopy maltodextrin beverage on gastric residual volume and patient's well-being: a randomised controlled trial.

Autor: Zulkifli MF; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Md Hashim MN; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia. drnizamkk@usm.my.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. drnizamkk@usm.my., Zahari Z; Faculty of Pharmacy, Universiti Sultan Zainal Abidin (UniSZA), Besut Campus, 22200, Besut, Terengganu, Malaysia. zalinazahari@unisza.edu.my., Wong MP; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Syed Abd Aziz SH; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Endoscopy Unit, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Yahya MM; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Wan Zain WZ; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Zakaria AD; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Ramely R; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Jien Yen S; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Othman MF; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia (USM), 16150, Kubang Kerian, Kelantan, Malaysia.; Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Nov 16; Vol. 13 (1), pp. 20078. Date of Electronic Publication: 2023 Nov 16.
DOI: 10.1038/s41598-023-47357-5
Abstrakt: Prolonged fasting prior to oesophagogastroduodenoscopy (OGDS) could be noxious to patients' well-being. Strict fasting protocol has been used prior to OGDS with the concern of reduced visibility or suboptimal endoscopic assessment. Maltodextrin beverages were also commonly used as the pre-operative carbohydrate loading in enhanced recovery after surgery (ERAS) protocol. Our study aimed to look for the effects of maltodextrin beverage 2 h before OGDS on gastric residual volume and patient's well-being scores. This was a single-blinded, stratified randomised controlled trial, comparing control group (A, received 400 ml of plain water) and carbohydrate loading group (B, received 400 ml of Carborie). The primary objectives were to measure the gastric residual volume (GRV) and patient's well-being scores using visual analogue scale (VAS) scores for hunger, thirst, anxiety, tiredness and general discomfort. Of 80 randomised patients, 78 completed the study (38 received plain water and 40 Carborie). The median (IQR) GRV was not significantly different between group A and B (5.0 ml (20) vs 4.0 ml (19), p = 0.777). Both groups showed significant reduction in VAS scores in all five parameters (p ≤ 0.001). There were no complications attributed to endoscopy in either group. Pre-endoscopy maltodextrin beverage is as safe as clear water with improved patient's well-being in both groups.Clinical Trial Registration: NCT05106933.
(© 2023. The Author(s).)
Databáze: MEDLINE
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