| Autor: |
Brémont S; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.; Institut Pasteur, National Reference Center for Corynebacteria of the Diphtheriae Complex, Paris, France., Passet V; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France., Hennart M; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France., Fonteneau L; Santé publique France, Saint-Maurice, France., Toubiana J; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.; Institut Pasteur, National Reference Center for Corynebacteria of the Diphtheriae Complex, Paris, France.; General pediatric and infectious diseases, Necker-enfants malades hospital, Université Paris Cité, Paris, France., Badell E; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.; Institut Pasteur, National Reference Center for Corynebacteria of the Diphtheriae Complex, Paris, France., Brisse S; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.; Institut Pasteur, National Reference Center for Corynebacteria of the Diphtheriae Complex, Paris, France. |
| Abstrakt: |
We describe 10 unlinked cases of Corynebacterium diphtheriae infection (nine cutaneous, one respiratory) in France in 2023 in persons travelling from Guinea, Mali, Senegal, Niger or Nigeria and Central African Republic. Four isolates were toxigenic. Seven genomically unrelated isolates were multidrug-resistant, including a toxigenic respiratory isolate with high-level resistance to macrolides and beta-lactams. The high rates of resistance, including against first-line agents, call for further microbiological investigations to guide clinical management and public health response in ongoing West African outbreaks. |
