Effects of Exogenous Erythropoietin on Rabbit ( Oryctolagus cuniculus ) Hematological and Biochemical Parameters.

Autor:	Levine JK; Comparative Medicine Branch, Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia., Seixas JN; Infectious Disease Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia., Ritter JM; Infectious Disease Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia., Liew AY; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Tansey CM; Comparative Medicine Branch, Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jazyk:	angličtina
Zdroj:	Comparative medicine [Comp Med] 2023 Dec 01; Vol. 73 (6), pp. 439-445. Date of Electronic Publication: 2023 Nov 15.
DOI:	10.30802/AALAS-CM-22-000107
Abstrakt:	Rabbits can develop anemia due to serial phlebotomy or secondary to induced disease states. This study evaluated the effects of a single injection and three consecutive injections of erythropoietin in rabbits at 150 IU/kg and 1,000 IU/kg in order to determine whether these dosages produce a sustained increase in hematocrit. Analysis of CBC and chemistry parameters showed significant elevation in hematocrit one week after administration of 1,000 IU/kg erythropoietin for three consecutive days. These results indicate that this dosage regimen can increase hematocrit in apparently healthy, nonanemic rabbits for one week.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu