Photobiomodulation therapy in the treatment of radiotherapy-related trismus of the head and neck.

Autor: Borges MMF; Division of Oral Pathology, Department of Dental Clinic, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil. marcelaborges4321@hotmail.com.; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil. marcelaborges4321@hotmail.com., Malta CEN; Division of Oral Pathology, Department of Dental Clinic, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil.; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil.; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil., Carlos ACAM; Division of Oral Pathology, Department of Dental Clinic, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil., Crispim AA; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil.; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil., de Moura JFB; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil., Rebouças LM; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil., Coelho da Silva BC; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil., de Albuquerque CGP; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil., de Barros Silva PG; Division of Oral Pathology, Department of Dental Clinic, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil.; Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil.; Hospital Haroldo Juaçaba, Ceará Cancer Institute, Fortaleza, Ceará, Brazil.
Jazyk: angličtina
Zdroj: Lasers in medical science [Lasers Med Sci] 2023 Nov 08; Vol. 38 (1), pp. 259. Date of Electronic Publication: 2023 Nov 08.
DOI: 10.1007/s10103-023-03920-0
Abstrakt: This study evaluated photobiomodulation therapy (PBMT) for treatment of trismus in patients undergoing radiotherapy for head and neck cancer (HNC). Sixteen patients, 10 men and 6 women, who had a mouth opening < 35 mm and underwent RT were included. The patients were evaluated daily before and after the PBMT application, measuring mouth opening and performing pain scores for the masticatory muscles using the visual analog scale (VAS). We used the infrared laser (~ 808 nm) extraorally, 0.1 W power, 3 J energy, 30 s (107 J/cm 2 ) per point, applied to temporalis anterior, masseter muscles, and temporomandibular joints (TMJ). An intraoral point was made in the trigonoretromolar region towards the medial pterygoid muscle. The mean mouth opening of the patients increased by more than 7 mm throughout the treatment. The pain scores on the initial days showed an immediate reduction after PBMT on the ipsilateral side in the muscles and TMJ. Throughout PBMT applications, there was a significant reduction in pain scores in all muscles and the TMJ. The radiation dose of all patients was above 40 Gy, which is the threshold dose for the risk of developing trismus. SPSS software was used and adopted a confidence of 95%. The Kolmogorov-Smirnov normality test, Wilcoxon test, and Spearman correlation were performed. PBMT controls muscular pain and reduced mouth opening limitation in HNC during radiotherapy. Further studies are needed to evaluate the preventive capacity of PBMT protocols for RT trismus-related HNC.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.)
Databáze: MEDLINE
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