Diagnosis of IRAK-4-deficiency by flow cytometric measurement of IκB-α degradation.

Autor: Frans G; Department of Microbiology, Immunology and Transplantation, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium.; Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium., Michiels B; Department of Microbiology, Immunology and Transplantation, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium.; Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium., Picard C; Necker Medical School, Paris Descartes University, Paris, France.; Study Center for Primary Immunodeficiencies, Necker-Enfants Malades Hospital, Assistance Publique Hôpitaux de Paris (APHP), Paris, France.; Imagine Institute, Paris Descartes University Paris, France.; Pediatric Hematology-Immunology Unit, Necker Hospital for Sick Children, AP-HP Paris, France., Ampofo L; Department of Pharmaceutical and Pharmacological Sciences, Therapeutic and Diagnostic Antibodies, KU Leuven, Leuven, Belgium., Raes M; Department of Pediatrics, Jessa Hospital, Hasselt, Belgium., Toelen J; Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium., Bucciol G; Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium.; Department of Microbiology, Immunology and Transplantation, Laboratory for Inborn Errors of Immunity, KU Leuven, Leuven, Belgium., van der Werff Ten Bosch J; Department of Pediatrics, Antwerp Hospital Network, Antwerp, Belgium., Moens L; Department of Microbiology, Immunology and Transplantation, Laboratory for Inborn Errors of Immunity, KU Leuven, Leuven, Belgium., Wuyts G; Department of Microbiology, Immunology and Transplantation, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium., Dillaerts D; Department of Microbiology, Immunology and Transplantation, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium., Casanova JL; Imagine Institute, Paris Descartes University Paris, France.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, and Pediatric Hematology-Immunology Unit, Necker Hospital for Sick Children Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, New York, NY, USA., Schrijvers R; Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Group, KU Leuven, Leuven, Belgium.; Department of General Internal Medicine, University Hospitals Leuven, Leuven, Belgium., Meyts I; Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium.; Department of Microbiology, Immunology and Transplantation, Laboratory for Inborn Errors of Immunity, KU Leuven, Leuven, Belgium., Bossuyt X; Department of Microbiology, Immunology and Transplantation, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium.; Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.
Jazyk: angličtina
Zdroj: Clinical chemistry and laboratory medicine [Clin Chem Lab Med] 2023 Nov 06; Vol. 62 (4), pp. e102-e105. Date of Electronic Publication: 2023 Nov 06 (Print Publication: 2024).
DOI: 10.1515/cclm-2023-0999
Databáze: MEDLINE