Aspergillus terreus Antibody Serosurveillance in Tyrol: A Population-Based, Cross-Sectional Study of a Healthy Population.

Autor: Steixner S; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Tirol, Austria., Vahedi Shahandashti R; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Tirol, Austria., Siller A; Central Institute for Blood Transfusion and Immunology, Tirol Kliniken GmbH, 6020 Innsbruck, Tirol, Austria., Ulmer H; Department of Medical Statistics, Informatics and Health Economics, Medical University of Innsbruck, 6020 Innsbruck, Tirol, Austria., Reider N; Department of Dermatology, Venereology and Allergology, Medical University of Innsbruck, 6020 Innsbruck, Tirol, Austria., Schennach H; Central Institute for Blood Transfusion and Immunology, Tirol Kliniken GmbH, 6020 Innsbruck, Tirol, Austria., Lass-Flörl C; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Tirol, Austria.
Jazyk: angličtina
Zdroj: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2023 Oct 12; Vol. 9 (10). Date of Electronic Publication: 2023 Oct 12.
DOI: 10.3390/jof9101008
Abstrakt: The rare, but emerging mold Aspergillus terreus is an important pathogen in some geographical areas, like Tyrol (Austria) and Houston (Texas). The reason for this high prevalence is unknown. The present serosurveillance study aimed to evaluate the trends in levels of A. terreus -specific IgG antibodies in various regions of Tyrol and to compare the results to the environmental spread of A. terreus in Tyrol. Therefore, 1058 serum samples from healthy blood donors were evaluated. Data revealed a significant difference between the Tyrolean Upland and Lowland. Moreover, female participants had higher A. terreus IgG antibody levels than male participants. The differences found in our study are consistent with the distributional differences in environmental and clinical samples described in previous studies, supporting that A. terreus IgG antibody levels reflect the environmental epidemiology of A. terreus in Tyrol.
Databáze: MEDLINE
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