Systematic review and meta-analysis of the global prevalence of sexually transmitted infections in people living with HIV and associated risk factors.

Autor: Ebrahimi M; Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Mehdizad N; Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Yeganeh-Sefidan F; Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Safarpour H; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Pagheh AS; Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran., Pouremamali A; Department of Medical Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran., Shiralizadeh S; Hamadan University of Medical Sciences, Hamadan, Iran., Ghodrati A; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Jafari S; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Shahrivar F; Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Heidarzadeh S; Department of Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran., Montazeri M; Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran., Yousef-Memar M; CICECO - Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal., Rodrigues-Oliveira SM; CICECO - Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal.; HMRI - Hunter Medical Research Institute, New Lambton, Australia., de-Lourdes-Pereira M; CICECO - Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal.; Department of Medical Sciences, University of Aveiro, Aveiro, Portugal., Beloukas A; National AIDS Reference Center of Southern Greece, Department of Public Health Policy, University of West Attica, Athens, Greece.; Molecular Microbiology and Immunology Lab, Department of Biomedical Sciences, University of West Attica, Athens, Greece., Hatam-Nahavandi K; School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran., Barac A; Clinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, Belgrade, Serbia., Shirvaliloo M; Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Ahmadpour E; Infectious and Tropical Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Parasitology and Mycology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Jazyk: angličtina
Zdroj: AIDS reviews [AIDS Rev] 2023; Vol. 26 (3), pp. 105-126.
DOI: 10.24875/AIDSRev.23000008
Abstrakt: People living with HIV (PLWH) constitute a vulnerable population for acquiring additional sexually transmitted infections (STIs). This study was conducted to provide a summary of the evidence on the global prevalence of STIs in PLWH with an emphasis on infectious agents, diagnostic methods, and related risk factors. PubMed, Scopus, and Web of Science were systematically searched to include records published from January 01, 1990, to January 31, 2022, and the Google Scholar search engine was used to check the search strategy. In total, 132 eligible studies reporting STIs in PLWH were included, enrolling subjects from 35 countries across five continents. The pooled proportion of STIs was estimated to be 30.23% (95% CI, 26.1-34.45%) in PLWH and 20.01% (95% CI, 17.17-23.01%) in HIV-negative patients. Our meta-analysis indicated that in PLWH, the pooled OR of STIs compared to HIV-negatives was 1.77 (95% CI: 1.58-1.98) (p < 0.0001). The pooled OR of STIs by viral infectious agents was highest in PLWH (52.19% [95% CI: 43.88-60.43]) compared with fungal (22.19% [95% CI: 15.64-29.53]), bacterial (19.07% [95% CI: 13.59-26.63]), and parasitic (14.05% [95% CI: 11.88-16.38]) infections. Our findings show that there is a rather significant frequency of STIs among PLWH. This study highlights the need for new programs for the detection, treatment, and prevention of STIs in this at-risk population.
(Copyright: © 2023 Permanyer.)
Databáze: MEDLINE