Saprochaete Capitata Peritonitis in a Non-neutropenic Patient Without Underlying Malignancies: A Case Report.
Autor: | Rahali FZ; Department of Clinical Laboratory, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Marrakesh, MAR., Bounani F; Department of Clinical Laboratory, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Marrakesh, MAR., Babokh F; Department of Clinical Laboratory, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Marrakesh, MAR., El Hakkouni A; Department of Biology/Department of Parasitology and Mycology, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Cadi Ayyad University, Marrakesh, MAR. |
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Jazyk: | angličtina |
Zdroj: | Cureus [Cureus] 2023 Sep 19; Vol. 15 (9), pp. e45568. Date of Electronic Publication: 2023 Sep 19 (Print Publication: 2023). |
DOI: | 10.7759/cureus.45568 |
Abstrakt: | Saprochaete capitata ( S. capitata ) is an opportunistic arthroconidial yeast-like fungus causing invasive infections in immunocompromised patients, mainly those with hematological malignancies and severe neutropenia. However, infections due to S. capitata are extremely rare in immunocompetent and non-neutropenic patients. Saprochaete spp. are microscopically characterized by arthroconidia with hyaline-septated hyphae. S. capitata is known to be intrinsically resistant to echinocandins and highly resistant to fluconazole. It is suggested to use amphotericin B or voriconazole (in monotherapy or in combination) as the gold standard treatment for S. capitata systemic infections. We report a rare case of S. capitata peritonitis with fatal outcome in a non-neutropenic patient without underlying malignancies. This case report highlights the value of direct microscopic examination and stained smears in a prompt preliminary diagnosis of S. capitata invasive fungal infections. We also aim to emphasize the importance of early initiation of appropriate antifungal treatment in patients with S. capitata systemic infections, thus improving their therapeutic outcome. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Rahali et al.) |
Databáze: | MEDLINE |
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