Analysis of some antispasmodic drugs: oxyphencyclimine and glycopyrronium bromide.

Autor: Ebeid MY, Moussa BA, Abdel Malak AA
Jazyk: angličtina
Zdroj: Pharmaceutisch weekblad. Scientific edition [Pharm Weekbl Sci] 1986 Oct 17; Vol. 8 (5), pp. 252-8.
DOI: 10.1007/BF01960069
Abstrakt: Oxyphencyclimine hydrochloride (via its tertiary amine group) and glycopyrronium bromide (via its quaternary ammonium group) were analysed by two different colorimetric methods. The first method depends on the dye-salt formation method using tropeolin ooo as the anionic dye and 1,2-dichloroethane as solvent for the extraction of the formed ion pairs. The coloured ion pairs have maximum absorption at 483-486 nm. The second method is based on the use of citric acid-acetic anhydride reagent. The coloured complex has maximum absorption at 562-565 nm.
Databáze: MEDLINE