Polyp detection in the cecum and ascending colon by dye based chromoendoscopy - Is its routine use justified?

Autor: Paiva RA; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil., Queiroz FL; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil., França Neto PR; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil., Costa BXMD; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil., Cardoso LAB; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil., Estrada DML; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil., Mota FFD; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil., Lacerda Filho A; - Hospital Felicio Rocho, Coloproctologia - Belo Horizonte - MG - Brasil.
Jazyk: English; Portuguese
Zdroj: Revista do Colegio Brasileiro de Cirurgioes [Rev Col Bras Cir] 2023 Oct 13; Vol. 50, pp. e20233562. Date of Electronic Publication: 2023 Oct 13 (Print Publication: 2023).
DOI: 10.1590/0100-6991e-20233562-en
Abstrakt: Introduction: colonoscopy is the best method for detecting polyps, with a reduction in colorectal cancer mortality of 29% and reaching 47% for distal tumors. However, it fails to demonstrate a significant reduction in proximal colon cancer mortality, and is the most common segment with interval neoplasm. The present study aimed to evaluate the impact on detection of polyps of a second sequential evaluation of cecum and ascending colon, with or without the use of indigo carmine chromoendoscopy.
Methods: prospective, non-randomized clinical trial. Patients were divided into two groups. The first (G1) underwent a routine colonoscopy, followed by a second endoscopy assessment of ascending colon and cecum. The second group (G2) underwent a routine colonoscopy, followed by a second assessment of the ascending colon and cecum with indigo carmine chromoendoscopy.
Results: In total, 203 patients were analyzed, 101 in the G1 and 102 in the G2. Newer polyps were identified in both groups after the second assessment with a significantly higher number of polyps detected in the patients in the G2 (p=0.0001). The number of patients who had at least one polyp in the two endoscopic assessments was significantly higher in the G2 (53 or 52% vs 27 or 26.7%, p=0.0002). In the second endoscopic assessment, the number of polyps found was also significantly higher in the G2 (50 or 76.9%) compared to the G1 (15 or 23.1%), p<0.0001.
Conclusions: the second assessment with dye-based chromoendoscopy increases the detection of polyps in the ascending colon and cecum.
Databáze: MEDLINE