Iodized Salt May Not Be Sufficient to Guarantee an Adequate Iodine Intake in Pregnant Women.

Autor:	Spina V; Mother and Infant Department Unit, ASL-Rieti, 02100 Rieti, Italy., Baldini E; Department of Surgery, 'Sapienza' University of Rome, 00185 Rome, Italy., Cardarelli S; Department of Surgery, 'Sapienza' University of Rome, 00185 Rome, Italy., Oliva C; Obstetrics and Gynaecology Unit, 'S. Camillo De Lellis' Hospital, 02100 Rieti, Italy., Venarubea S; Clinical Pathology Laboratory Unit, 'S. Camillo De Lellis' Hospital, 02100 Rieti, Italy., Faraoni F; Pediatrics and Neonatology Unit, 'S. Camillo De Lellis' Hospital, 02100 Rieti, Italy., Pastore G; Obstetrics and Gynaecology Unit, 'S. Camillo De Lellis' Hospital, 02100 Rieti, Italy., Tittoni R; Obstetrics and Gynaecology Unit, 'S. Camillo De Lellis' Hospital, 02100 Rieti, Italy., Musella A; Obstetrics and Gynaecology Unit, 'S. Camillo De Lellis' Hospital, 02100 Rieti, Italy., Squarcella A; Obstetrics and Gynaecology Unit, 'S. Camillo De Lellis' Hospital, 02100 Rieti, Italy., Lori E; Department of Surgery, 'Sapienza' University of Rome, 00185 Rome, Italy., Renzi E; Mother and Infant Department Unit, ASL-Rieti, 02100 Rieti, Italy., Feroci R; Mother and Infant Department Unit, ASL-Rieti, 02100 Rieti, Italy., Mastrodonato F; Mother and Infant Department Unit, ASL-Rieti, 02100 Rieti, Italy., Ciferri F; Mother and Infant Department Unit, ASL-Rieti, 02100 Rieti, Italy., Virili C; Department of Medico-Surgical Sciences and Biotechnologies, 'Sapienza' University of Rome, 04100 Latina, Italy., Centanni M; Department of Medico-Surgical Sciences and Biotechnologies, 'Sapienza' University of Rome, 04100 Latina, Italy., Fabiani C; Mother and Infant Department, 'Sandro Pertini' Hospital, 00157 Rome, Italy., Rago R; Mother and Infant Department, 'Sandro Pertini' Hospital, 00157 Rome, Italy., Schiavi MC; Obstetrics and Gynaecology Unit, 'Sandro Pertini' Hospital, 00157 Rome, Italy., Palazzetti P; Obstetrics and Gynaecology Unit, 'Sandro Pertini' Hospital, 00157 Rome, Italy., D'Armiento E; Department of Internal Medicine and and Medical Specialties, 'Sapienza' University of Rome, 00185 Rome, Italy., Cantisani V; Department of Radiological and Oncological Sciences and Pathological Anatomy, 'Sapienza' University of Rome, 00185 Rome, Italy.; Teleradiology Complex Unit, ASL-Rieti, 02100 Rieti, Italy., Sorrenti S; Department of Surgery, 'Sapienza' University of Rome, 00185 Rome, Italy., Ulisse S; Department of Surgery, 'Sapienza' University of Rome, 00185 Rome, Italy.
Jazyk:	angličtina
Zdroj:	Nutrients [Nutrients] 2023 Sep 27; Vol. 15 (19). Date of Electronic Publication: 2023 Sep 27.
DOI:	10.3390/nu15194182
Abstrakt:	Adequate iodine intake is of crucial importance in pregnancy to meet the thyroid hormone needs of both mother and fetus. In the present study, undertaken as a part of the surveillance actions following the introduction in Italy of a national salt iodination program in 2005, the iodine intake was investigated in 123 pregnant women and 49 control women living in the same area of central Italy. All the participants were screened for urinary iodine concentration (UIC), serum level of thyrotropin, free-thyroxine, free-triiodothyronine, and thyroid volume. Moreover, they were provided with a questionnaire on the use of iodine-containing salt or supplements. Control women had a median UIC of 102 µg/L, consistent with an iodine sufficiency, while in pregnant women the median UIC value was 108 µg/L, lower than the endorsed UIC of 150 µg/L. In addition, pregnant women showed a significantly increased median thyroid volume compared to controls. Interestingly, the median UIC did not differ between pregnant women not using iodine-containing salt or supplements and those regularly consuming iodized salt alone, while pregnant women with a daily intake of iodine-containing supplements had an adequate median UIC (168 µg/L). In conclusion, the data reported here showed that pregnant women and their fetuses are still exposed to the detrimental effects of iodine deficiency and that the consumption of iodine-containing supplements should be recommended in pregnancy.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu