Impact of COVID-19 critical illness on functional status, fatigue symptoms, and health-related quality of life one-year after hospital discharge: a systematic review and meta-analysis.

Autor:	Gesser AF; Master's Program in Physiotherapy, University of the State of Santa Catarina, Florianópolis, Brazil., Campos ML; Master's Program in Physiotherapy, University of the State of Santa Catarina, Florianópolis, Brazil., Artismo RS; Master's Program in Physiotherapy, University of the State of Santa Catarina, Florianópolis, Brazil.; Postgraduate Program in Human Movement Sciences, University of the State of Santa Catarina, Florianópolis, Brazil., Karloh M; Master's Program in Physiotherapy, University of the State of Santa Catarina, Florianópolis, Brazil.; Department of Physiotherapy, Center of Health and Sport Sciences, University of the State of Santa Catarina, Florianópolis, Brazil., Matte DL; Master's Program in Physiotherapy, University of the State of Santa Catarina, Florianópolis, Brazil.; Postgraduate Program in Human Movement Sciences, University of the State of Santa Catarina, Florianópolis, Brazil.; Department of Physiotherapy, Center of Health and Sport Sciences, University of the State of Santa Catarina, Florianópolis, Brazil.
Jazyk:	angličtina
Zdroj:	Disability and rehabilitation [Disabil Rehabil] 2024 Sep; Vol. 46 (18), pp. 4086-4097. Date of Electronic Publication: 2023 Oct 11.
DOI:	10.1080/09638288.2023.2266365
Abstrakt:	Purpose: To estimate the prevalence and severity of impairments in functional status, fatigue, and health-related quality of life (HRQoL) among critical COVID-19 survivors one-year after hospital discharge. Methods: A systematic review was conducted following PRISMA statement and registered in PROSPERO (CRD42021258356), with searches in eight databases. Observational studies were selected. The prevalence meta-analysis of abnormalities was performed using random-effects models. Risk of bias was evaluated using the National Heart, Lung, and Blood Institute tool. Results: Twenty studies were included, with data collected between 12 and 13.5 months after hospital discharge and a total of 1828 participants. Of these, 71% were men, and 77.7% were intubated in the intensive care unit (ICU). Impairments and sequelae were identified in varying prevalence and degrees, with greater impact on functional capacity and physical components of fatigue and HRQoL. The prevalence of abnormalities of 32.3% [95% CI 23.9; 41.9] found in the meta-analysis is substantially high. Most studies were classified as having fair and poor quality. Conclusion: Critical COVID-19 survivors experience impairments in functional status, fatigue, and HRQoL to varying degrees one-year after hospital discharge, particularly among patients who stayed in the ICU and on MV for a prolonged period.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu