Ag/g-C 3 N 4 nanocomposite: Green fabrication and its application as a catalyst in the synthesis of new series of depsipeptides as biologically active compounds and investigation on their anti-breast cancer activity.

Autor: Shahi F; Department of Chemistry, College of Science, University of Guilan, Rasht Zip Code 41335, I.R., Iran., Kamali F; Department of Chemistry, College of Science, University of Guilan, Rasht Zip Code 41335, I.R., Iran., Sharifzaheh B; Department of Engineering Science, Faculty of Technology and Engineering, East of Guilan, University of Guilan, Rudsar-Vajargah, 44891-63157, Iran., Shirini F; Department of Chemistry, College of Science, University of Guilan, Rasht Zip Code 41335, I.R., Iran. Electronic address: Shirini@guilan.ac.ir.
Jazyk: angličtina
Zdroj: Bioorganic chemistry [Bioorg Chem] 2023 Dec; Vol. 141, pp. 106804. Date of Electronic Publication: 2023 Aug 22.
DOI: 10.1016/j.bioorg.2023.106804
Abstrakt: In this study, we bring forward a green and novel eco-friendly strategy for the fabrication of Ag/g-C 3 N 4 nanocomposite via a fast in-situ generation method using Ferula Gummosa extracts as both stabilizer and reducing agent. Ag/g-C 3 N 4 nanocomposite was analyzed by Fourier transform infrared spectra (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX-MAP), and transmission electron microscopy (TEM). After procurement and characterization, the catalytic activity of the prepared reagent was surveyed in the synthesis of a new series of depsipeptides using aspirin/ketoprofen, cyclohexyl isocyanide, and aryl aldehydes at ambient temperature in EtOH/H 2 O as a green media. Taking into account the economic and environmental facets, the method bestows some advantages such as using plant extracts as green media for the preparation of Ag nanoparticles, simple work-up procedure, mild reaction conditions, short reaction times, and high yields of the products. Additionally, the Ag/g-C 3 N 4 nanocomposite catalyst can be recycled effectually and reused several times without a substantial loss in reactivity.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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