Pancreatic duct pressure: A review of technical aspects and clinical significance.

Autor: Singh A; Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, United States., Bush N; Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, United States., Bhullar FA; Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, United States., Faghih M; Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, United States., Moreau C; Division of Gastroenterology, University of Texas Health San Antonio, San Antonio, TX, United States., Mittal R; Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, United States., Seo JH; Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, United States., Talukdar R; Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India., Lakhtakia S; Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India., Singh VK; Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, United States., Akshintala VS; Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, United States. Electronic address: vakshin1@jhmi.edu.
Jazyk: angličtina
Zdroj: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] [Pancreatology] 2023 Nov; Vol. 23 (7), pp. 858-867. Date of Electronic Publication: 2023 Sep 29.
DOI: 10.1016/j.pan.2023.09.141
Abstrakt: Pancreatic duct pressure (PDP) dynamics comprise an intricately modulated system that helps maintain homeostasis of pancreatic function. It is affected by various factors, including the rate of pancreatic fluid secretion, patency of the ductal system, sphincter of Oddi function, and pancreatic fluid characteristics. Disease states such as acute and chronic pancreatitis can alter the normal PDP dynamics. Ductal hypertension or increased PDP is suspected to be involved in the pathogenesis of pancreatic pain, endocrine and exocrine pancreatic insufficiency, and recurrent pancreatitis. This review provides a comprehensive appraisal of the available literature on PDP, including the methods used in the measurement and clinical implications of elevated PDP.
(Copyright © 2023 IAP and EPC. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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