Increasing Incidence and Decreasing Mortality of Melanoma in Elderly Adults: An Epidemiologic Study in Olmsted County, Minnesota.

Autor:	Proffer SL; Department of Dermatology, Mayo Clinic School of Graduate Medical Education, Rochester, Minnesota., Reinhart JP; Department of Dermatology, Mayo Clinic School of Graduate Medical Education, Rochester, Minnesota., Campbell EH; Department of Dermatology, Mayo Clinic School of Graduate Medical Education, Rochester, Minnesota., Crum OM; Department of Dermatology, Mayo Clinic School of Graduate Medical Education, Rochester, Minnesota., Gibson LE; Department of Dermatology, Division of Dermatopathology, Mayo Clinic, Rochester, Minnesota., Brewer JD; Department of Dermatology, Division of Dermatologic Surgery, Mayo Clinic, Rochester, Minnesota., Demer AM; Department of Dermatology, Division of Dermatologic Surgery, Mayo Clinic, Rochester, Minnesota.
Jazyk:	angličtina
Zdroj:	Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2024 Feb 01; Vol. 50 (2), pp. 125-130. Date of Electronic Publication: 2023 Oct 03.
DOI:	10.1097/DSS.0000000000003972
Abstrakt:	Background and Objective: Primary cutaneous melanoma incidence is increasing in elderly individuals. This population-based cohort examines incidence and mortality rates among adults aged 61 years and older with cutaneous melanoma. Materials and Methods: Using the Rochester Epidemiology Project, patients aged 61 years of age or older with a first lifetime diagnosis of cutaneous melanoma between January 1, 1970 and December 31, 2020 were identified. Results: The age- and sex-adjusted incidence rate increased from 16.4 (95% CI, 8.2-24.6) per 100,000 person-years in 1970 to 1979 to 201.5 (95% CI, 185.1-217.8) per 100,000 person-years in 2011 to 2020 (12.3-fold increase). There was a 16.0x increase in males and an 8.5× increase in females. Melanoma incidence has stabilized in males (1.2-fold increase, p = .11) and continues to significantly increase in females (2.7-fold increase, p < .001). Older age at diagnosis was significantly associated with an increased risk of death (HR 1.23 per 5-year increase in age at diagnosis, 95% CI, 1.02-1.47). Conclusion: Melanoma incidence continues to increase since 1970. The incidence has risen in elderly females, but has stabilized in males. Mortality has decreased throughout this period. (Copyright © 2023 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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