Cactus flour (Opuntia ficus-indica) reduces brain lipid peroxidation and anxious-like behavior in old Wistar rats.

Autor: Moura RL; Program of Natural Sciences and Biotechnology, Federal University of Campina Grande, Cuité, Paraiba, Brazil., Dutra LMG; Program of Food Science and Technology, Federal University of Paraíba, João Pessoa, PB, Brazil. Electronic address: lara-dutra@hotmail.com., Nascimento MDVSD; Federal University of Campina Grande, Cuité, Paraiba, Brazil., de Oliveira JCN; Federal University of Campina Grande, Cuité, Paraiba, Brazil., Viera VB; Laboratory of Bromatology, Department of Nutrition, Federal University of Campina Grande, Cuité, CG, Brazil., Dantas BS; Program of Food Science and Technology, Federal University of Paraíba, João Pessoa, PB, Brazil., Costa RG; Technologists Training Center - Campus IV, Department of Agriculture, Federal University of Paraíba, Brazil., da Silva MS; Post-Graduate Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Paraíba, João Pessoa, PB, Brazil., de Medeiros AN; Center for Agricultural Sciences - Campus III, Department of Animal Science, Federal University of Paraíba, Brazil., Nascimento YMD; Post-Graduate Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Paraíba, João Pessoa, PB, Brazil., Tavares JF; Post-Graduate Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Paraíba, João Pessoa, PB, Brazil., Soares JKB; Program of Natural Sciences and Biotechnology, Federal University of Campina Grande, Cuité, Paraiba, Brazil.
Jazyk: angličtina
Zdroj: Physiology & behavior [Physiol Behav] 2023 Dec 01; Vol. 272, pp. 114360. Date of Electronic Publication: 2023 Sep 29.
DOI: 10.1016/j.physbeh.2023.114360
Abstrakt: The aim of this research was to evaluate the effect of cactus flour on the anxious-like behavior and cerebral lipid peroxidation in elderly rats (18 months of life). The rats were divided into four groups (n=10). control (CG) - received the AIN-93M ration. P5%. P10% and P15%. treated with the AIN-93M ration with the addition of 5, 10 and 15% of cactus flour respectively. In the elevated plus maze (EPM) groups P5%, P10% and P15% remained longer in the open arms. P15% remained longer in this region and less time in the closed arms. No significant differences were observed between the groups regarding the time the rats remained in the center of the apparatus. P5%. P10% and P15% performed a greater number of head dips. Regarding the open field animals P5%. P10% and P15% performed a greater number of rearing and stayed for a longer time in the center of the apparatus with P15% being the group that remained for the longest time when compared to the other groups. There was no difference in locomotion and grooming. As for the light-dark box. P15% spent more time in the light part. less time in the dark part and performed a smaller number of transitions. P5%. P10% and P15% had the lowest concentrations of brain lipid peroxidation. Our data demonstrated that consumption of cactus flour by rats promoted anxiolytic effects and minimized brain lipid peroxidation in aging. Given the above, it can be deduced that cactus pear can contribute to the prevention and/or treatment of anxiety in the aging phase.Due to its concentrations of mono and polyunsaturated fatty acids, soluble fibers and antioxidant contents such as vitamin E and selenium.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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