Thyroid disorders and male sexual dysfunction.

Autor: Morenas R; Department of Urology, Section of Andrology, Tulane University School of Medicine, New Orleans, LA, USA., Singh D; Department of Urology, Section of Andrology, Tulane University School of Medicine, New Orleans, LA, USA., Hellstrom WJG; Department of Urology, Section of Andrology, Tulane University School of Medicine, New Orleans, LA, USA. whellst@tulane.edu.
Jazyk: angličtina
Zdroj: International journal of impotence research [Int J Impot Res] 2024 Jun; Vol. 36 (4), pp. 333-338. Date of Electronic Publication: 2023 Sep 26.
DOI: 10.1038/s41443-023-00768-4
Abstrakt: Though early research suggested that thyroid hormones were not involved with the testes, male spermatogenesis, or erectile function, investigations on this topic over the past few decades have increased and shed new light. A literature review of studies conducted between 1963 and 2022 regarding male sexual dysfunction (SD) and thyroid disorders was performed to define the diagnostic consideration, pathophysiology, and management of SD secondary to thyroid dysregulation. This article provides evidence and interpretation of prior clinical and preclinical studies and contextualizes these studies for clinical practice. Clinical manifestations of SDs included erectile and ejaculatory dysfunction, impaired spermatogenesis, and disruption of the hypothalamic-pituitary-gonadal axis. Our aim of this communication was to perform a literature review detailing the impact of thyroid disorders on male SD. We hope to provide a framework for practicing urologists, endocrinologists, or general practitioners when evaluating patients with concurrent thyroid and male SD. It is important to recognize that thyroid disorders can be an important part of the pathophysiology of male SD in patients. Future research studies are needed to further elucidate the mechanisms involved.
(© 2023. The Author(s), under exclusive licence to Springer Nature Limited.)
Databáze: MEDLINE
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