[Subthalamic deep brain stimulation in a case of idiopathic Parkinson's disease and schizophrenia].

Autor:	Fernández-Pajarín G; Hospital Clínico Universitario de Santiago, Santiago de Compostela, España.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, España., Ares-Pensado B; Hospital Clínico Universitario de Santiago, Santiago de Compostela, España.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, España., Koukoulis A; Complejo Hospitalario de Vigo, Vigo, España., Jiménez-Martín I; Hospital Clínico Universitario de Santiago, Santiago de Compostela, España.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, España., Sesar A; Hospital Clínico Universitario de Santiago, Santiago de Compostela, España.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, España.
Jazyk:	Spanish; Castilian
Zdroj:	Revista de neurologia [Rev Neurol] 2023 Oct 01; Vol. 77 (7), pp. 167-170.
DOI:	10.33588/rn.7707.2023060
Abstrakt:	Introduction: Parkinson's disease (PD) and schizophrenia can coexist. Antipsychotics block striatal D2 receptors, which inevitably aggravates the manifestations of PD. Case Report: We report the case of a male patient with idiopathic Parkinson's disease and schizophrenia, with poor tolerance to minimal doses of levodopa, who underwent a dramatic improvement after bilateral subthalamic deep brain stimulation (DBS-STN). DBS-STN was taken into consideration here, due to the severity of this particular case, as the only possible way to achieve motor improvement. Conclusions: The diagnosis of idiopathic PD was confirmed despite antidopaminergic treatment. DBS-STN can be considered a treatment option for disabling manifestations of PD, provided that a careful selection of patients is carried out..
Databáze:	MEDLINE
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