Nutritional status in perianal Crohn's disease: are we underestimating the impact?

Autor:	Alves Martins BA; Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Brasília, Brazil.; Department of Colorectal Surgery, Hospital Universitário de Brasília, Brasília, Brazil., Filho OM; Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Brasília, Brazil.; Department of Colorectal Surgery, Hospital Universitário de Brasília, Brasília, Brazil., Lopes ACB; IBD Unit, Department of Gastroenterology, Hospital Universitário de Brasília, Brasília, Brazil., de Faria RJ; IBD Unit, Department of Gastroenterology, Hospital Universitário de Brasília, Brasília, Brazil., Silva C; Department of Nutrition and Dietetics, Hospital Universitário de Brasília, Brasília, Brazil., Lemos GO; Multiprofessional Nutritional Therapy Team, Hospital Universitário de Brasília, Brasília, Brazil., Silveira DB; Department of Colorectal Surgery, Hospital de Base-IGESDF, Brasília, Brazil., de Sousa JB; Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Brasília, Brazil.; Department of Colorectal Surgery, Hospital Universitário de Brasília, Brasília, Brazil.
Jazyk:	angličtina
Zdroj:	Frontiers in nutrition [Front Nutr] 2023 Sep 07; Vol. 10, pp. 1271825. Date of Electronic Publication: 2023 Sep 07 (Print Publication: 2023).
DOI:	10.3389/fnut.2023.1271825
Abstrakt:	Symptomatic perianal disease is common in patients with Crohn's disease (CD), and perianal fistulas represent the primary form of anal involvement. This type of involvement is associated with a poor prognosis and a disabling course. The treatment is challenging and involves both surgical and medical approaches. Despite combined therapy, a significant portion of patients may still require proctectomy to control the symptoms. Consequently, investigating factors that may influence the outcome of perianal disease remains a priority area of research in CD. Nutritional deficiencies are well documented among CD patients with luminal forms of involvement and are closely related to poor clinical outcomes, therapy response, and postoperative complications. As a result, leading guidelines recommend regular nutritional assessment and correction of nutritional deficiencies in patients requiring a surgical approach. Despite these recommendations and the high rate of surgeries among CD patients with perianal disease, there is a shortage of studies addressing the real impact of nutritional status on the course and outcomes of perianal disease. This knowledge gap underscores the importance of further research to understand better and improve the management of perianal CD. This narrative review aims to provide an overview of nutritional status assessment and the influence of nutritional status on the outcomes of patients with perianal CD. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Alves Martins, Filho, Lopes, de Faria, Silva, Lemos, Silveira and de Sousa.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu