| Autor: |
Weidlich S; Department of Internal Medicine II, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany., Schellberg S; Novopraxis Berlin, Mohrenstr 6, 10117 Berlin, Germany., Scholten S; Praxis Hohenstaufenring Köln, Richard-Wagner-Str 9-11, 50674 Cologne, Germany., Schneider J; Department of Internal Medicine II, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany., Lee M; Department of Internal Medicine II, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany., Rothe K; Institute for Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Trogerstr. 30, 81675 Munich, Germany., Wantia N; Institute for Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Trogerstr. 30, 81675 Munich, Germany., Spinner CD; Department of Internal Medicine II, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 80802 Munich, Germany., Noe S; Department of Internal Medicine II, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.; MVZ München am Goetheplatz, Waltherstr. 32, 80807 Munich, Germany. |
| Abstrakt: |
Sexually transmitted infections (STIs) are increasing among men who have sex with men (MSM). Screening can improve the detection and outcome of asymptomatic STIs in high-risk populations. Self-sampling may be a resource-optimized strategy; however, its diagnostic reliability compared to testing by healthcare professionals (HCPs) requires further investigation. In this prospective, multicenter cohort study in a high-income country, asymptomatic MSM with a sexual risk profile for STIs were included. Sequential swabs for STI nucleic acid-based diagnosis of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) were performed after randomization, either through self-sampling or HCP-performed sampling. Baseline demographic information, sexual risk behavior, and acceptance and feedback on self-sampling were recorded using an electronic questionnaire. Out of 236 asymptomatic MSM, 47 individuals (19.9%) tested positive for CT and/or NG through self- or HCP-performed sampling. For CT, the sensitivity was 93.3% for both sampling methods, while for NG, it was 90.0% for self-sampling and 95.0% for HCP-performed sampling. Our study demonstrates that self-sampling for asymptomatic STIs has a comparable diagnostic outcome to HCP-performed sampling, with high acceptance in high-risk MSM. |
