The evaluation of Candida-related central line-related bloodstream infections in pediatric cancer patients: A pre- and post-intervention study.

Autor: Devrim İ; Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Celebi MY; Department of Pediatric Infectious Diseases, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Karakaya N; Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Sahinkaya S; Department of Pediatric Infectious Diseases, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Acar SO; Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Cem E; Department of Pediatric Infectious Diseases, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Demirağ B; Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Oruc Y; Department of Pediatric Infectious Diseases, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Kara AA; Department of Pediatric Infectious Diseases, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Oymak Y; Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Karapınar TH; Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey., Bayram N; Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey.
Jazyk: angličtina
Zdroj: Journal of infection prevention [J Infect Prev] 2023 Sep; Vol. 24 (5), pp. 219-222. Date of Electronic Publication: 2023 Aug 26.
DOI: 10.1177/17571774231191334
Abstrakt: Aim/objections: The purpose of this study was to assess the efficacy of a central line maintenance bundle in preventing catheter-related (implanted venous access devices, port) Candida bloodstream infections.
Methods: The study encompassed two distinct time periods, namely, pre-bundle and bundle. The number of catheter-related bloodstream infections (CRBSI) episodes per catheter days for each timeframe was determined.
Findings/results: Upon implementation of the central line bundle, the rate of CRBSI reduced significantly from 4.27 per 1000 central line days in the pre-bundle period to 1.0 per 1000 central line days in the bundle period ( p < .001).
Discussion: Using a central line bundle to avoid CRBSIs in pediatric cancer patients with ports led to a significant decrease in Candida species-related CRBSIs.
Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© The Author(s) 2023.)
Databáze: MEDLINE