| Autor: |
Mitchell JK; Department of Chemistry, New York University, New York, New York 10003, United States., Hussain WA; Department of Chemistry, New York University, New York, New York 10003, United States., Bansode AH; Department of Chemistry, New York University, New York, New York 10003, United States., O'Connor RM; Department of Chemistry, New York University, New York, New York 10003, United States., Wise DE; Department of Chemistry, New York University, New York, New York 10003, United States., Choe MH; Department of Chemistry, New York University, New York, New York 10003, United States., Parasram M; Department of Chemistry, New York University, New York, New York 10003, United States. |
| Abstrakt: |
Herein, we report a protocol for the anaerobic oxidation of alcohols, amines, aldehydes, and imines promoted by photoexcited nitroarenes. Mechanistic studies support the idea that photoexcited nitroarenes undergo double hydrogen atom transfer (HAT) steps with alcohols and amines to provide the respective ketone and imine products. In the presence of aldehydes and imines, successive HAT and oxygen atom transfer (OAT) events occur to yield carboxylic acids and amides, respectively. This transformation is amenable to a continuous-photoflow setup, which led to reduced reaction times. |
