Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast.

Autor:	Masamsetti VP; Embryology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia.; The University of Sydney, Faculty of Medicine and Health, School of Medical Sciences, NSW 2006, Australia., Tam PPL; Embryology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia.; The University of Sydney, Faculty of Medicine and Health, School of Medical Sciences, NSW 2006, Australia.
Jazyk:	angličtina
Zdroj:	Cell reports methods [Cell Rep Methods] 2023 Aug 28; Vol. 3 (8), pp. 100575. Date of Electronic Publication: 2023 Aug 28 (Print Publication: 2023).
DOI:	10.1016/j.crmeth.2023.100575
Abstrakt:	Iwatsuki and colleagues have generated self-renewing pluripotent stem cells from the pre-gastrulation epiblast of the rat embryo and from other cellular sources: rat embryonic stem cells (rESCs) and epiblast-like cells derived from the rESCs. These rat epiblast-derived stem cells (rEpiSCs) display germ-line competence that is characteristic of mouse formative stem cells and early signature of specification of germ layer lineages typical of primed state mouse epiblast stem cells. Competing Interests: The authors declare no competing interests. (© 2023 The Author(s).)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu