SepT, a novel protein specific to multicellular cyanobacteria, influences peptidoglycan growth and septal nanopore formation in Anabaena sp. PCC 7120.

Autor:	Velázquez-Suárez C; Instituto de Bioquímica Vegetal y Fotosíntesis, CSIC and Universidad de Sevilla , Seville, Spain., Springstein BL; Institute of General Microbiology, Kiel University , Kiel, Germany., Nieves-Morión M; Instituto de Bioquímica Vegetal y Fotosíntesis, CSIC and Universidad de Sevilla , Seville, Spain., Helbig AO; AG Proteomics & Bioanalytics, Institute for Experimental Medicine, Christian-Albrechts-Universität zu Kiel , Kiel, Germany., Kieninger A-K; Department of Microbiology/Organismic Interactions, University of Tübingen , Tübingen, Germany., Maldener I; Department of Microbiology/Organismic Interactions, University of Tübingen , Tübingen, Germany., Nürnberg DJ; Institute of Experimental Physics and Dahlem Centre of Plant Sciences, Free University of Berlin , Berlin, Germany., Stucken K; Department of Food Engineering, Universidad de La Serena , La Serena, Chile., Luque I; Instituto de Bioquímica Vegetal y Fotosíntesis, CSIC and Universidad de Sevilla , Seville, Spain., Dagan T; Institute of General Microbiology, Kiel University , Kiel, Germany., Herrero A; Instituto de Bioquímica Vegetal y Fotosíntesis, CSIC and Universidad de Sevilla , Seville, Spain.
Jazyk:	angličtina
Zdroj:	MBio [mBio] 2023 Oct 31; Vol. 14 (5), pp. e0098323. Date of Electronic Publication: 2023 Aug 31.
DOI:	10.1128/mbio.00983-23
Abstrakt:	Importance: Multicellular organization is a requirement for the development of complex organisms, and filamentous cyanobacteria such as Anabaena represent a paradigmatic case of bacterial multicellularity. The Anabaena filament can include hundreds of communicated cells that exchange nutrients and regulators and, depending on environmental conditions, can include different cell types specialized in distinct biological functions. Hence, the specific features of the Anabaena filament and how they are propagated during cell division represent outstanding biological issues. Here, we studied SepT, a novel coiled-coil-rich protein of Anabaena that is located in the intercellular septa and influences the formation of the septal specialized structures that allow communication between neighboring cells along the filament, a fundamental trait for the performance of Anabaena as a multicellular organism. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu