[Molecular genetic features of meningiomas].

Autor:	Makashova ES; Burdenko Neurosurgical Center, Moscow, Russia.; Loginov Moscow Clinical Scientific Practical Center, Moscow, Russia., Lasunin NV; Burdenko Neurosurgical Center, Moscow, Russia., Galkin MV; Burdenko Neurosurgical Center, Moscow, Russia., Zolotova SV; Burdenko Neurosurgical Center, Moscow, Russia., Karandasheva KO; Bochkov Medical Genetic Research Center, Moscow, Russia., Golanov AV; Burdenko Neurosurgical Center, Moscow, Russia.
Jazyk:	English; Russian
Zdroj:	Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2023; Vol. 87 (4), pp. 101-106.
DOI:	10.17116/neiro202387041101
Abstrakt:	Meningioma is the most common primary tumor of the central nervous system. Traditional classification is based on histological properties of tumors and distinguishes different grades of meningioma malignancy. However, knowledge about different molecular mechanisms of tumor provided new data on genetic features of meningiomas. The authors analyze current available data on the main driver mutations, new classifications based on molecular genetic characteristics and potential targets for therapy.
Databáze:	MEDLINE
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