| Autor: |
Al-Qadi M; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Centre de Formation Médicale du Nouveau-Brunswick, Université de Sherbrooke and Université de Moncton, New Brunswick, NB, Canada., Hussain A; Department of Ophthalmology & Visual Sciences, Dalhousie University, Halifax, Nova Scotia, Canada. |
| Jazyk: |
angličtina |
| Zdroj: |
Orbit (Amsterdam, Netherlands) [Orbit] 2024 Aug; Vol. 43 (4), pp. 549-554. Date of Electronic Publication: 2023 Aug 23. |
| DOI: |
10.1080/01676830.2023.2248621 |
| Abstrakt: |
Graves'-associated upper eyelid retraction (GAUER) is the commonest manifestation of orbitopathy in adults. Surgical management typically follows a 3-step staged approach commencing with orbital decompression. The rationale behind this is that certain surgical interventions can influence the parameters and outcomes of subsequent procedures. We performed a systematic review and meta-analysis evaluating the effects of orbital decompression on GAUER in adult patients with Graves' orbitopathy. All original English, non-pediatric studies meeting the study inclusion criteria from the last 20 years were included. The characteristics of margin reflex distance 1 (MRD-1) pre- and post-orbital decompression of 688 orbits were collected, and a meta-analysis of 472 orbits was performed. The average reduction in MRD-1 across 688 orbits was found to be 0.40 mm. Meta-analysis of 6 applicable articles demonstrated that orbital decompression decreases MRD-1 by an average of 0.35 mm ( n = 472, p = .007, 95% CI = [0.08, 0.63]). This study demonstrates that although statistically significant, orbital decompression does not appear to have a clinically significant effect on GAUER . This has implications for clinical practice, namely the likely requirement of eyelid surgery following or in combination with orbital decompression, and the importance of counselling patients on this preoperatively. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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