Autor: |
Prasad R; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California., Narsana NK; Division of Infectious Diseases, Department of Internal Medicine, Davis School of Medicine, University of California, Sacramento, California., Ajayi AA; Critical Care Medicine and Pulmonary Disease, Montage Health, Monterey, California., Wang H; Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio., Patel J; Division of Oncology, Department of Medicine, Stanford Health Care, Stanford, California., Ho DY; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California., Banaei N; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California.; Department of Pathology, Stanford University School of Medicine, Stanford, California., Blackburn BG; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California. |
Abstrakt: |
Leptospirosis is typically a self-limited febrile illness; when it occurs, meningitis usually develops early in the course. Here, we describe a patient who had engaged in freshwater activities in Kauai that was immunocompromised due to a history of mantle cell lymphoma, autologous hematopoietic cell transplant, and hypogammaglobulinemia. He developed leptospiral meningoencephalitis 11 weeks after illness onset and persistently detectable Leptospira DNA in blood and cerebrospinal fluid along with ongoing clinical illness, despite appropriate treatment. |