Assessment of COVID-19-related olfactory dysfunction and its association with psychological, neuropsychiatric, and cognitive symptoms.

Autor:	Jegatheeswaran L; Department of Ear, Nose and Throat Surgery, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, United Kingdom., Gokani SA; Rhinology and ENT Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom., Luke L; Department of Ear, Nose and Throat Surgery, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, United Kingdom.; Rhinology and ENT Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom., Klyvyte G; Rhinology and ENT Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom., Espehana A; Rhinology and ENT Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom., Garden EM; Rhinology and ENT Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom., Tarantino A; Department of Ear, Nose and Throat Surgery, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, United Kingdom., Al Omari B; Department of Ear, Nose and Throat Surgery, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, United Kingdom., Philpott CM; Department of Ear, Nose and Throat Surgery, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, United Kingdom.; Rhinology and ENT Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom.
Jazyk:	angličtina
Zdroj:	Frontiers in neuroscience [Front Neurosci] 2023 Aug 04; Vol. 17, pp. 1165329. Date of Electronic Publication: 2023 Aug 04 (Print Publication: 2023).
DOI:	10.3389/fnins.2023.1165329
Abstrakt:	Purpose of Review: To provide a detailed overview of the assessment of COVID-19-related olfactory dysfunction and its association with psychological, neuropsychiatric, and cognitive symptoms. Recent Findings: COVID-19-related olfactory dysfunction can have a detrimental impact to the quality of life of patients. Prior to the COVID-19 pandemic, olfactory and taste disorders were a common but under-rated, under-researched and under-treated sensory loss. The pandemic has exacerbated the current unmet need for accessing good healthcare for patients living with olfactory disorders and other symptoms secondary to COVID-19. This review thus explores the associations that COVID-19 has with psychological, neuropsychiatric, and cognitive symptoms, and provide a framework and rationale for the assessment of patients presenting with COVID-19 olfactory dysfunction. Summary: Acute COVID-19 infection and long COVID is not solely a disease of the respiratory and vascular systems. These two conditions have strong associations with psychological, neuropsychiatric, and cognitive symptoms. A systematic approach with history taking and examination particularly with nasal endoscopy can determine the impact that this has on the patient. Specific olfactory disorder questionnaires can demonstrate the impact on quality of life, while psychophysical testing can objectively assess and monitor olfaction over time. The role of cross-sectional imaging is not yet described for COVID-19-related olfactory dysfunction. Management options are limited to conservative adjunctive measures, with some medical therapies described. Competing Interests: CP reports grants from NIHR, ESPRC, and ENT UK, personal fees from Stryker, Abbott, and Olympus, outside the submitted work, and Trustee of Fifth Sense. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Jegatheeswaran, Gokani, Luke, Klyvyte, Espehana, Garden, Tarantino, Al Omari and Philpott.)
Databáze:	MEDLINE
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