| Autor: |
Zheng J; College of Pharmaceutical Science, Dali University, Dali, China., Shang M; College of Pharmaceutical Science, Dali University, Dali, China., Dai G; College of Pharmaceutical Science, Dali University, Dali, China., Dong J; College of Pharmaceutical Science, Dali University, Dali, China., Wang Y; College of Pharmaceutical Science, Dali University, Dali, China.; Formula-Pattern Research Center, School of Traditional Chinese Medicine, Jinan University, Guangzhou, Guangdong, China., Duan B; College of Pharmaceutical Science, Dali University, Dali, China. |
| Jazyk: |
angličtina |
| Zdroj: |
Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2024 Nov; Vol. 64 (32), pp. 12103-12126. Date of Electronic Publication: 2023 Aug 21. |
| DOI: |
10.1080/10408398.2023.2248246 |
| Abstrakt: |
Momordica charantia L. is a well-known medicine and food homology plant with high pharmaceutical and nutritional values. Polysaccharides are carbohydrate polymers connected by glycosidic bonds, one of the key functional ingredients of M. charantia . Recently, M. charantia polysaccharides (MCPs) have attracted much attention from industries and researchers due to their anti-oxidant, anti-tumor, anti-diabetes, anti-bacteria, immunomodulatory, neuroprotection, and organ protection activities. However, the development and utilization of MCPs-based functional foods and medicines were hindered by the lack of a deeper understanding of the structure-activity relationship (SAR), structural modification, applications, and safety of MCPs. Herein, we provide an overview of the extraction, purification, structural characterization, bioactivities, and mechanisms of MCPs. Besides, SAR, toxicities, application, and influences of the modification associated with bioactivities are spotlighted, and the potential development and future study direction are scrutinized. This review provides knowledge and research underpinnings for the further research and application of MCPs as therapeutic agents and functional food additives. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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