Agta hunter-gatherer oral microbiomes are shaped by contact network structure.

Autor:	Musciotto F; Dipartimento di Fisica e Chimica, Università di Palermo, Palermo, Italy.; Department of Anthropology, University of Zurich, Zurich, Switzerland., Dobon B; Department of Anthropology, University of Zurich, Zurich, Switzerland.; Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Barcelona, Spain., Greenacre M; Department of Economics and Business, Universitat Pompeu Fabra & Barcelona Graduate School of Economics, Barcelona, Spain.; Faculty of Biosciences, Fisheries and Economics, University of Tromsø, Norway., Mira A; Department of Health and Genomics, Center for Advanced Research in Public Health, FISABIO Foundation, Valencia, Spain.; CIBER Center for Epidemiology and Public Health, Madrid, Spain., Chaudhary N; Department of Archaeology, University of Cambridge, Cambridge, UK., Salali GD; Department of Anthropology, University College London, London, UK., Gerbault P; Department of Genetics and Evolution, University of Geneva, Geneva, Switzerland., Schlaepfer R; Department of Anthropology, University of Zurich, Zurich, Switzerland., Astete LH; Lyceum of the Philippines University, Intramuros, Manila, Philippines., Ngales M; Lyceum of the Philippines University, Intramuros, Manila, Philippines., Gomez-Gardenes J; GOTHAM Lab, Institute for Biocomputation and Physics of Complex Systems, and Department of Condensed Matter Physics, University of Zaragoza, Zaragoza, Spain.; Center for Computational Social Science, Kobe University, Kobe, Japan., Latora V; School of Mathematical Sciences, Queen Mary University of London, London, UK.; Dipartimento di Fisica ed Astronomia, Università di Catania and INFN, Catania, Italy.; Complexity Science Hub Vienna, Vienna, Austria., Battiston F; Department of Anthropology, University of Zurich, Zurich, Switzerland.; Department of Network and Data Science, Central European University, Vienna, Austria., Bertranpetit J; Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Barcelona, Spain., Vinicius L; Department of Anthropology, University of Zurich, Zurich, Switzerland.; Department of Anthropology, University College London, London, UK., Migliano AB; Department of Anthropology, University of Zurich, Zurich, Switzerland.; Department of Anthropology, University College London, London, UK.
Jazyk:	angličtina
Zdroj:	Evolutionary human sciences [Evol Hum Sci] 2023 Feb 23; Vol. 5, pp. e9. Date of Electronic Publication: 2023 Feb 23 (Print Publication: 2023).
DOI:	10.1017/ehs.2023.4
Abstrakt:	Here we investigate the effects of extensive sociality and mobility on the oral microbiome of 138 Agta hunter-gatherers from the Philippines. Our comparisons of microbiome composition showed that the Agta are more similar to Central African BaYaka hunter-gatherers than to neighbouring farmers. We also defined the Agta social microbiome as a set of 137 oral bacteria (only 7% of 1980 amplicon sequence variants) significantly influenced by social contact (quantified through wireless sensors of short-range interactions). We show that large interaction networks including strong links between close kin, spouses and even unrelated friends can significantly predict bacterial transmission networks across Agta camps. Finally, we show that more central individuals to social networks are also bacterial supersharers. We conclude that hunter-gatherer social microbiomes are predominantly pathogenic and were shaped by evolutionary tradeoffs between extensive sociality and disease spread. Competing Interests: The authors declare none. (© The Author(s) 2023.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu