| Autor: |
Gulian JM, Dalmasso C, Pontier F, Gonard V |
| Jazyk: |
angličtina |
| Zdroj: |
Chemotherapy [Chemotherapy] 1986; Vol. 32 (5), pp. 399-403. |
| DOI: |
10.1159/000238442 |
| Abstrakt: |
The effects of ceftriaxone, a 'third-generation' cephalosporin, on bilirubin-serum albumin complexes were investigated. This study was performed on human adult samples at various bilirubin-albumin ratios. Ceftriaxone caused a decrease of unconjugated bilirubin and simultaneously an increase of erythrocyte-bound bilirubin. These variations were proportionally more important for low concentrations of antibiotic, including therapeutic values. It was concluded that ceftriaxone competes with bilirubin and displaces it from albumin-binding sites. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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