Imaging Modalities and Their Findings in Patients With Complex Regional Pain Syndrome: A Review.

Autor:	Tangella AV; Internal Medicine, King George Hospital and Andhra Medical College, Visakhapatnam, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Jul 11; Vol. 15 (7), pp. e41747. Date of Electronic Publication: 2023 Jul 11 (Print Publication: 2023).
DOI:	10.7759/cureus.41747
Abstrakt:	Complex regional pain syndrome (CRPS) is a systemic or regional pain pathology associated with the nondermatomal or dermatomal distribution of excruciating intolerable pain, which might be triggered by an insignificant or weak stimulus or sometimes without any. Its symptoms encompass neurological, musculoskeletal, dermatological, and vascular realms. It is usually preceded by an episode of nerve injury or intervention set in numerous circumstances ranging from trauma to surgeries to chronic diseases. CRPS has been shrouded in a veil of mystery  and was called a psychological  phenomenon without any proper organic basis when it was described by Ambroise Pare initially. This led to disproportionately fewer research investments into this disease. Given the great advancement of diagnostic modalities since its inception, researchers and physicians have been trying to identify the physiological basis for it and have succeeded. Numerous pathophysiological pathways have been involved in this disease, but all of them point toward the possibility of improper pain processing at various levels of the pain pathway along with brain plasticity leading to aberrant neuronal circuitry between different segments of the sensory cortex, basal ganglia, prefrontal cortex, and insula. This paper explores the various studies done to evaluate the role of different imaging modalities, ranging from three-phase bone scintigraphy (TPBS) to diffusion traction imaging (DTI). Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Tangella et al.)
Databáze:	MEDLINE
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