Cellulose microcrystalline: A promising ecofriendly approach to control Culex quinquefasciatus larvae.

Autor: Souza SS; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil., Gomes AR; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil., Guimarães ATB; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil., Rodrigues ASL; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil., de Matos LP; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil., Dos Santos Mendonça J; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil., da Luz TM; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil., Matos SGDS; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil., Rahman MS; Department of Environmental Science and Disaster Management, Noakhali Science and Technology University, Noakhali 3814, Bangladesh., Ragavendran C; Saveetha Dental College and Hospitals (SIMATS), Saveetha University Chennai, Tamil Nadu, India., Senthil-Nathan S; Division of Biopesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tirunelveli, Tamil Nadu 627 412, India., Guru A; Department of Cariology, Saveetha Dental College and Hospitals, SIMATS, Chennai 600 077, Tamil Nadu, India., Rakib MRJ; Noakhali Science and Technology University, Noakhali, Bangladesh., Mubarak NM; Petroleum and Chemical Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan BE1410, Brunei Darussalam; Department of Biosciences, Saveetha School of Engineering, Saveetha institute of Medical and Technical Sciences, Chennai, India., Rahman MM; Jahangirnagar University Dhaka-1342, Bangladesh., Rocha TL; Laboratory of Environmental Biotechnology and Ecotoxicology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Goiás, Brazil., Islam ARMT; Department of Disaster Management, Begum Rokeya University, Rangpur 5400, Bangladesh., Malafaia G; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus. Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil. Electronic address: guilhermeifgoiano@gmail.com.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2023 Nov 25; Vol. 901, pp. 165952. Date of Electronic Publication: 2023 Aug 01.
DOI: 10.1016/j.scitotenv.2023.165952
Abstrakt: The growing use of synthetic chemical compounds/substances in vector control of mosquitoes, associated with their adverse effects on the environment and non-target organisms, has demanded the development of eco-friendly alternatives. In this context, this study aimed to evaluate the larvicidal action of different cellulose microcrystalline (CMs) concentrations and investigate their toxicity mechanisms in Culex quinquefasciatus fourth instar larvae as a model species. Probit analysis revealed that the median lethal concentrations (LC 50 ) for 24 h and 36 h exposure were 100 and 58.29 mg/L, respectively. We also showed that such concentrations induced a redox imbalance in the larvae, marked by an increase in the production of reactive oxygen species (ROS) and thiobarbituric acid reactive substances (TBARS), as well as a reduction in the activity of superoxide dismutase (SOD) and catalase (CAT). Furthermore, different alterations in the external morphology of the larvae were associated with the ingestion of CMs. On the other hand, exposure of adult zebrafish (Danio rerio) to LC 50 24h and LC 50 36h for seven days did not induce any behavioral changes or alterations mutagenic, genotoxic, biochemical, or in the production of cytokines IFN-γ and IL-10. Thus, taken together, our study demonstrates for the first time that the use of CMs can constitute a promising strategy in the control of C. quinquefasciatus larvae, combining insecticidal efficiency with an "eco-friendly" approach in the fight against an important mosquito vector of several human diseases.
Competing Interests: Declaration of competing interest We confirm that there are no known conflicts of interest associated with this work, and there has been no significant financial support for this work that could have influenced its outcome. Furthermore, we ensure that the manuscript has been read and approved by all named authors and that there are no other persons who satisfied the criteria for authorship but are not listed. We further confirm that all have approved the order of authors listed in the manuscript of us. Due care has been taken to ensure the integrity of the work.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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