Does Physical Activity Confound Race Differences in Osteoarthritis-Related Functional Limitation?

Autor: Vina ER; Temple University, Philadelphia, Pennsylvania, and University of Arizona, Tucson., Patel P; Temple University, Philadelphia, Pennsylvania., Grest CV; Temple University, Philadelphia, Pennsylvania., Kwoh CK; University of Arizona College of Medicine, Tucson., Jakiela JT; University of Delaware, Newark., Bye T; University of Delaware, Newark., White DK; University of Delaware, Newark.
Jazyk: angličtina
Zdroj: Arthritis care & research [Arthritis Care Res (Hoboken)] 2024 Feb; Vol. 76 (2), pp. 200-207. Date of Electronic Publication: 2023 Oct 25.
DOI: 10.1002/acr.25209
Abstrakt: Objective: This study sought to determine the extent to which physical activity confounds the relation between race and the incidence of osteoarthritis (OA)-related functional limitation.
Methods: OA Initiative study participants with or at increased risk of knee OA who wore an accelerometer were included. Race was self-reported. Average time spent in moderate to vigorous physical activity (minutes per day) based on ActiGraph uniaxial accelerometer data was assessed. Functional limitation was based on the following: (1) inability to achieve a community walking speed (1.2 m/s) standard, (2) slow walking speed (<1.0 m/s), and (3) low physical functioning based on a Western Ontario and McMaster Universities OA Index (WOMAC) physical function score greater than 28 of 68.
Results: African American (AA) participants (n = 226), compared with White participants (n = 1348), had a higher likelihood of developing functional limitation based on various measures. When adjusted for time in moderate to vigorous physical activity, the association between AA race and inability to walk a community walking speed slightly decreased (from relative risk [RR] 2.15, 95% confidence interval [95% CI] 1.64-2.81, to RR 1.99, 95% CI 1.51-2.61). Association between AA race and other measures of functional limitation mildly decreased (slow walking speed: from RR 2.06, 95% CI 1.40-3.01, to RR 1.82, 95% CI 1.25-2.63; low physical functioning: from RR 3.44, 95% CI 1.96-6.03, to RR 3.10, 95% CI 1.79-5.39). When further adjusted for demographic and other clinical variables, only the association between race and low physical functioning (WOMAC) significantly decreased and no longer met statistical significance.
Conclusion: Greater physical activity is unlikely to completely make up for race differences in OA-related functional limitation, and other barriers to health equity need to be addressed.
(© 2023 American College of Rheumatology.)
Databáze: MEDLINE
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