Impact of COVID-19 Diagnosis on Mortality in Patients with Ischemic Stroke Admitted during the 2020 Pandemic in Italy.

Autor: De Luca L; Department of Cardio-Thoracic and Vascular Medicine and Surgery, Division of Cardiology, A.O. San Camillo-Forlanini, 00152 Rome, Italy.; Faculty of Medicine and Dentistry, UniCamillus-Saint Camillus International University of Health Sciences, 00131 Rome, Italy., D'Errigo P; National Centre for Global Health, Italian National Institute of Health, 00161 Rome, Italy., Rosato S; National Centre for Global Health, Italian National Institute of Health, 00161 Rome, Italy., Badoni G; National Centre for Global Health, Italian National Institute of Health, 00161 Rome, Italy., Giordani B; Italian National Agency for Regional Healthcare Services, 00187 Rome, Italy., Mureddu GF; Division of Cardiology, San Giovanni Addolorata Hospital, 00100 Rome, Italy., Tavilla A; National Center for Disease Prevention and Health Promotion, Italian National Institute of Health, 00161 Rome, Italy., Seccareccia F; National Centre for Global Health, Italian National Institute of Health, 00161 Rome, Italy., Baglio G; Italian National Agency for Regional Healthcare Services, 00187 Rome, Italy.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2023 Jul 08; Vol. 12 (14). Date of Electronic Publication: 2023 Jul 08.
DOI: 10.3390/jcm12144560
Abstrakt: Aims: The impact of the COVID-19 pandemic on the event rate of patients with ischemic stroke has been poorly investigated. We sought to evaluate the impact of the COVID-19 infection on mortality in patients with ischemic stroke admitted during the 2020 pandemic in Italy.
Methods: We analyzed a nationwide, comprehensive, and universal administrative database of patients who were admitted for ischemic stroke during and after the national lockdown for the COVID-19 infection in 2020, and the equivalent periods over the previous 5 years in Italy. The 2020 observed hospitalization and mortality rates of stroke patients with and without COVID-19 infection were compared with the expected rates, in accordance with the trend of the previous 5 years.
Results: During the period of observation, 300,890 hospitalizations for ischemic stroke occurred in Italy. In 2020, 41,302 stroke patients (1102 with concomitant COVID-19 infection) were admitted at 771 centers. The rate of admissions for ischemic stroke during the 2020 pandemic was markedly reduced compared with previous years (percentage change vs. 2015: -23.5). Based on the 5 year trend, the 2020 expected 30 day and 1 year mortality rates were 9.8% and 23.9%, respectively, and the observed incidence of death rates were 12.2% and 26.7%, respectively (both p < 0.001). After multiple corrections, higher rates of mortality were observed among patients admitted for stroke with a concomitant COVID-19 diagnosis.
Conclusions: During the COVID-19 pandemic in 2020 in Italy, the rate of hospitalizations for ischemic stroke was dramatically reduced, although both the 30 day and 1 year mortality rates increased compared with the previous 5 year trend.
Databáze: MEDLINE
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