Developing a National-Scale Exposure Index for Combined Environmental Hazards and Social Stressors and Applications to the Environmental Influences on Child Health Outcomes (ECHO) Cohort.

Autor: Martenies SE; Department of Kinesiology and Community Health, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA., Zhang M; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA., Corrigan AE; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA., Kvit A; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA., Shields T; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA., Wheaton W; Research Triangle Institute, Research Triangle Park, NC 27709, USA., Around Him D; Child Trends, Bethesda, MD 20814, USA., Aschner J; Department of Pediatrics, Hackensack Meridian School of Medicine, Nutley, NJ 07110, USA.; Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Talavera-Barber MM; Avera Research Institute, Sioux Falls, SD 57105, USA., Barrett ES; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ 08854, USA., Bastain TM; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Bendixsen C; Marshfield Clinic Research Institute, Marshfield, WI 54449, USA., Breton CV; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Bush NR; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA 94143, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA., Cacho F; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Camargo CA Jr; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Carroll KN; Department of Pediatrics, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Carter BS; Department of Pediatrics-Neonatology, Children's Mercy Hospital, Kansas City, MO 64108, USA., Cassidy-Bushrow AE; Department of Public Health Sciences, Henry Ford Health, Detroit, MI 48202, USA., Cowell W; Department of Pediatrics, New York University Grossman School of Medicine, New York, NY 10016, USA., Croen LA; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA., Dabelea D; Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Duarte CS; New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA., Dunlop AL; Department of Obstetrics and Gynecology, Emory University School of Medicine, Atlanta, GA 30322, USA., Everson TM; Gangarosa Department of Environmental Health, Emory University Rollins School of Public Health, Atlanta, GA 30322, USA., Habre R; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Hartert TV; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA., Helderman JB; Department of Pediatrics, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Hipwell AE; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA., Karagas MR; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH 03756, USA., Lester BM; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI 02903, USA., LeWinn KZ; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA 94143, USA., Magzamen S; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA., Morello-Frosch R; Department of Environmental Science, Policy and Management and School of Public Health, University of California Berkeley, Berkeley, CA 94720, USA., O'Connor TG; Departments of Psychiatry, Psychology, Neuroscience, and Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY 41642, USA., Padula AM; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94158, USA., Petriello M; Institute of Environmental Health Sciences and Department of Pharmacology, Wayne State University, Detroit, MI 48202, USA., Sathyanarayana S; Seattle Children's Research Institute, Seattle, WA 98105, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98195, USA., Stanford JB; Department of Pediatrics, Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA., Woodruff TJ; Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94158, USA., Wright RJ; Department of Pediatrics, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kress AM; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Jazyk: angličtina
Zdroj: International journal of environmental research and public health [Int J Environ Res Public Health] 2023 Jul 10; Vol. 20 (14). Date of Electronic Publication: 2023 Jul 10.
DOI: 10.3390/ijerph20146339
Abstrakt: Tools for assessing multiple exposures across several domains (e.g., physical, chemical, and social) are of growing importance in social and environmental epidemiology because of their value in uncovering disparities and their impact on health outcomes. Here we describe work done within the Environmental influences on Child Health Outcomes (ECHO)-wide Cohort Study to build a combined exposure index. Our index considered both environmental hazards and social stressors simultaneously with national coverage for a 10-year period. Our goal was to build this index and demonstrate its utility for assessing differences in exposure for pregnancies enrolled in the ECHO-wide Cohort Study. Our unitless combined exposure index, which collapses census-tract level data into a single relative measure of exposure ranging from 0-1 (where higher values indicate higher exposure to hazards), includes indicators for major air pollutants and air toxics, features of the built environment, traffic exposures, and social determinants of health (e.g., lower educational attainment) drawn from existing data sources. We observed temporal and geographic variations in index values, with exposures being highest among participants living in the West and Northeast regions. Pregnant people who identified as Black or Hispanic (of any race) were at higher risk of living in a "high" exposure census tract (defined as an index value above 0.5) relative to those who identified as White or non-Hispanic. Index values were also higher for pregnant people with lower educational attainment. Several recommendations follow from our work, including that environmental and social stressor datasets with higher spatial and temporal resolutions are needed to ensure index-based tools fully capture the total environmental context.
Databáze: MEDLINE