| Autor: |
Alkilzy M; Department of Preventive and Pediatric Dentistry, University of Greifswald, 17475 Greifswald, Germany., Qadri G; Department of Orthodontic and Pediatric Dentistry, Arab American University, Jenin P.O. Box 240, Palestine., Splieth CH; Department of Preventive and Pediatric Dentistry, University of Greifswald, 17475 Greifswald, Germany., Santamaría RM; Department of Preventive and Pediatric Dentistry, University of Greifswald, 17475 Greifswald, Germany. |
| Jazyk: |
angličtina |
| Zdroj: |
Biomimetics (Basel, Switzerland) [Biomimetics (Basel)] 2023 Jul 04; Vol. 8 (3). Date of Electronic Publication: 2023 Jul 04. |
| DOI: |
10.3390/biomimetics8030290 |
| Abstrakt: |
The recent understanding of the etiology and pathology of dental caries has shifted its treatment from invasive drill and fill conventional strategies to noninvasive and/or minimally invasive approaches. Guided tissue regeneration (GTR) is a well-established therapeutic approach in medicine and periodontal and oral surgery. Recently, the concept of biomimetic regeneration has been further expanded to treat the loss of hard dental tissues. Self-assembling peptides have emerged as a promising biomaterial for biomimetic regeneration due to their ability to construct a protein scaffold in the body of early carious lesions and provide a matrix that promotes remineralization. This review article accompanies the development of self-assembling peptide P 11 -4 for the treatment of initial carious lesions. In vitro and in vivo studies on the safety, clinical applicability, and efficacy of P 11 -4 are discussed. Furthermore, different treatment options and potential areas of application are presented. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
