Magnetometer-Detected Nuclear Magnetic Resonance of Photochemically Hyperpolarized Molecules.

Autor:	Chuchkova L; Institut für Physik, Johannes Gutenberg Universität-Mainz, 55128 Mainz, Germany.; Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, 55128 Mainz, Germany., Bodenstedt S; ICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels (Barcelona), Spain., Picazo-Frutos R; Institut für Physik, Johannes Gutenberg Universität-Mainz, 55128 Mainz, Germany.; Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, 55128 Mainz, Germany., Eills J; Institute for Bioengineering of Catalonia, 08028 Barcelona, Spain., Tretiak O; Institut für Physik, Johannes Gutenberg Universität-Mainz, 55128 Mainz, Germany.; Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, 55128 Mainz, Germany., Hu Y; Institut für Physik, Johannes Gutenberg Universität-Mainz, 55128 Mainz, Germany.; Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, 55128 Mainz, Germany.; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China., Barskiy DA; Institut für Physik, Johannes Gutenberg Universität-Mainz, 55128 Mainz, Germany.; Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, 55128 Mainz, Germany., de Santis J; ICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels (Barcelona), Spain., Tayler MCD; ICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels (Barcelona), Spain., Budker D; Institut für Physik, Johannes Gutenberg Universität-Mainz, 55128 Mainz, Germany.; Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, 55128 Mainz, Germany.; Department of Physics, University of California, Berkeley, California 94720-7300, United States., Sheberstov KF; Institut für Physik, Johannes Gutenberg Universität-Mainz, 55128 Mainz, Germany.; Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, 55128 Mainz, Germany.
Jazyk:	angličtina
Zdroj:	The journal of physical chemistry letters [J Phys Chem Lett] 2023 Aug 03; Vol. 14 (30), pp. 6814-6822. Date of Electronic Publication: 2023 Jul 24.
DOI:	10.1021/acs.jpclett.3c01310
Abstrakt:	Photochemically induced dynamic nuclear polarization (photo-CIDNP) enables nuclear spin ordering by irradiating samples with light. Polarized spins are conventionally detected via high-field chemical-shift-resolved NMR (above 0.1 T). In this Letter, we demonstrate in situ low-field photo-CIDNP measurements using a magnetically shielded fast-field-cycling NMR setup detecting Larmor precession via atomic magnetometers. For solutions comprising mM concentrations of the photochemically polarized molecules, hyperpolarized 1 H magnetization is detected by pulse-acquired NMR spectroscopy. The observed NMR line widths are about 5 times narrower than normally anticipated in high-field NMR and are systematically affected by light irradiation during the acquisition period, reflecting a reduction of the transverse relaxation time constant, T 2 *, on the order of 10%. Magnetometer-detected photo-CIDNP spectroscopy enables straightforward observation of spin-chemistry processes in the ambient field range from a few nT to tens of mT. Potential applications of this measuring modality are discussed.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu