Magnetic nanoflowers: a hybrid platform for enzyme immobilization.

Autor: Patil PD; Department of Basic Science & Humanities, SVKM'S NMIMS Mukesh Patel School of Technology Management & Engineering, Mumbai, Maharashtra, India., Kelkar RK; Department of Biotechnology Engineering, Kolhapur Institute of Technology's College of Engineering (Autonomous), Kolhapur, India., Patil NP; Department of Biotechnology Engineering, Kolhapur Institute of Technology's College of Engineering (Autonomous), Kolhapur, India., Pise PV; Department of Biological Engineering, Indian Institute of Technology, Gandhinagar, Gandhinagar, India., Patil SP; Department of Biotechnology, National Institute of Technology, Tadepalligudam, India., Patil AS; Department of Biotechnology Engineering, Kolhapur Institute of Technology's College of Engineering (Autonomous), Kolhapur, India., Kulkarni NS; Department of Biotechnology Engineering, Kolhapur Institute of Technology's College of Engineering (Autonomous), Kolhapur, India., Tiwari MS; Department of Chemical Engineering, SVKM'S NMIMS Mukesh Patel School of Technology Management & Engineering, Mumbai, Maharashtra, India., Phirke AN; Department of Chemical Engineering, SVKM'S NMIMS Mukesh Patel School of Technology Management & Engineering, Mumbai, Maharashtra, India., Nadar SS; Department of Chemical Engineering, Institute of Chemical Technology, Mumbai, India.
Jazyk: angličtina
Zdroj: Critical reviews in biotechnology [Crit Rev Biotechnol] 2024 Aug; Vol. 44 (5), pp. 795-816. Date of Electronic Publication: 2023 Jul 16.
DOI: 10.1080/07388551.2023.2230518
Abstrakt: The use of organic-inorganic hybrid nanoflowers as a support material for enzyme immobilization has gained significant attention in recent years due to their high stability, ease of preparation, and enhanced catalytic activity. However, a major challenge in utilizing these hybrid nanoflowers for enzyme immobilization is the difficulty in handling and separating them due to their low density and high dispersion. To address this issue, magnetic nanoflowers have emerged as a promising alternative enzyme immobilization platform due to their easy separation, structural stability, and ability to enhance catalytic efficiency. This review focuses on different methods for designing magnetic nanoflowers, as well as future research directions. Additionally, it provides examples of enzymes immobilized in the form of magnetic nanoflowers and their applications in environmental remediation, biosensors, and food industries. Finally, the review discusses possible ways to improve the material for enhanced catalytic activity, structural stability, and scalability.
Databáze: MEDLINE