Prenatal diagnosis of Poland-Möbius syndrome by multimodality fetal imaging.

Autor: Nguyen GV; Creighton University School of Medicine, Omaha, NE, USA., Goncalves LF; Department of Radiology, Phoenix Children's, 1919 E. Thomas Rd, Phoenix, AZ, 85016, USA. lgoncalves@phoenixchildrens.com.; Department of Child Health, University of Arizona College of Medicine, Phoenix, AZ, USA. lgoncalves@phoenixchildrens.com.; Department of Radiology, University of Arizona College of Medicine, Phoenix, AZ, USA. lgoncalves@phoenixchildrens.com.; Department of Radiology, Creighton University School of Medicine, Phoenix, AZ, USA. lgoncalves@phoenixchildrens.com., Vaughn J; Department of Radiology, Phoenix Children's, 1919 E. Thomas Rd, Phoenix, AZ, 85016, USA.; Department of Child Health, University of Arizona College of Medicine, Phoenix, AZ, USA.; Department of Radiology, University of Arizona College of Medicine, Phoenix, AZ, USA.; Department of Radiology, Creighton University School of Medicine, Phoenix, AZ, USA.; Department of Neuroradiology, Barrow Neurological Institute at Phoenix Children's, Phoenix, AZ, USA., Friedman N; Department of Radiology, Phoenix Children's, 1919 E. Thomas Rd, Phoenix, AZ, 85016, USA.; Department of Neurology, Barrow Neurological Institute at Phoenix Children's, Phoenix, AZ, USA., Wickland J; Department of Child Health, University of Arizona College of Medicine, Phoenix, AZ, USA.; Department of Neonatology, Phoenix Children's, Phoenix, AZ, USA., Cornejo P; Department of Radiology, Phoenix Children's, 1919 E. Thomas Rd, Phoenix, AZ, 85016, USA.; Department of Child Health, University of Arizona College of Medicine, Phoenix, AZ, USA.; Department of Radiology, University of Arizona College of Medicine, Phoenix, AZ, USA.; Department of Radiology, Creighton University School of Medicine, Phoenix, AZ, USA.; Department of Radiology, Mayo Clinic, Scottsdale, AZ, USA.
Jazyk: angličtina
Zdroj: Pediatric radiology [Pediatr Radiol] 2023 Sep; Vol. 53 (10), pp. 2144-2148. Date of Electronic Publication: 2023 Jul 10.
DOI: 10.1007/s00247-023-05712-8
Abstrakt: We describe prenatal diagnosis of Poland-Möbius syndrome using a combination of ultrasound and MRI. Poland syndrome was diagnosed based on absence of the pectoralis muscles associated with dextroposition of the fetal heart and elevation of the left diaphragm. Associated brain anomalies that led to the diagnosis of Poland-Möbius syndrome, included ventriculomegaly, hypoplastic cerebellum, tectal beaking, and a peculiar flattening of the posterior aspect of the pons and medulla oblongata, which has been reported by postnatal diffusion tensor imaging studies as a reliable neuroimaging marker for Möbius syndrome. Since abnormalities of cranial nerves VI and VII may be difficult to detect prenatally, careful attention to the appearance of the brain stem as illustrated in the current report may aid in the prenatal diagnosis of Möbius syndrome.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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