Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study.

Autor: Azzolini C; Department of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, Italy., Di Nicola M; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami 33136, FL, USA., Pozzo Giuffrida F; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.; Ophthalmological Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy., Cappelli F; Department of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, Italy., Bellina C; Department of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, Italy., Viola F; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.; Ophthalmological Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy., Chelazzi P; Department of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, Italy.
Jazyk: angličtina
Zdroj: Life (Basel, Switzerland) [Life (Basel)] 2023 May 25; Vol. 13 (6). Date of Electronic Publication: 2023 May 25.
DOI: 10.3390/life13061253
Abstrakt: The purpose of the present study was to document pathological findings on retromode imaging in choroidal nevi and evaluate its diagnostic validity, using the confocal scanning laser ophthalmoscope Nidek Mirante (cSLO). A total of 41 choroidal nevi from 41 patients were included. All patients underwent multicolor fundus (mCF), infrared reflectance (IR), green fundus autofluorescence (FAF), dark-field (DF) and retromode (RM) imaging and optical coherence tomography (OCT) scans. We investigated retromode images to evaluate choroidal nevus features by comparing the results with those of mCF, IR, FAF, DF and OCT. In 100% of available images, retromode scanning laser ophthalmoscopy was able to detect choroidal nevi with a characteristic "hypo-retro-reflective" pattern, even the cases not visible on mCF, IR and FAF images. It also made it possible to delineate the margins of lesions with the highest rate of sharpness and accuracy among the imaging modalities examined. These findings seem to demonstrate how RM-SLO is an innovative diagnostic tool to detect and follow up choroidal nevi in a fast, reliable and non-invasive way.
Databáze: MEDLINE
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