Chorioamnionitis secondary to Ureaplasma parvum infection: a case report.
| Autor: | Moreno-Flores A; Hospital Universitario Lucus Augusti, Lugo, Spain., Domínguez-Landesa M; Hospital Universitario Lucus Augusti, Lugo, Spain., Vázquez-López MG; Hospital Universitario Lucus Augusti, Lugo, Spain., Sante-Fernández L; Hospital Universitario Lucus Augusti, Lugo, Spain. |
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| Jazyk: | English; Spanish; Castilian |
| Zdroj: | Advances in laboratory medicine [Adv Lab Med] 2023 Feb 15; Vol. 4 (1), pp. 128-132. Date of Electronic Publication: 2023 Feb 15 (Print Publication: 2023). |
| DOI: | 10.1515/almed-2023-0004 |
| Abstrakt: | Objectives: Ureaplasma species are the most frequently isolated microorganisms in cases of spontaneous preterm labor, premature rupture of the membranes, or chorioamnionitis. Case Presentation: A woman at 28 +6 weeks of gestation with no apparent history of interest presented at the hospital with contractions. Upon suspicion of chorioamnionitis, the patient was admitted for a low segment transverse cesarean section, which was completed without any complications. The patient was discharged at 7 days. The newborn remained stable and showed no clinical signs of infection. However, on suspicion of chorioamnionitis, empirical treatment with intravenous ampicillin (2 g every 6 h) and gentamicin (5 mg/kg once daily) was initiated. Samples of pharyngeal/tonsillar, ear, and anal/rectal exudates were collected. At 24 h, all samples were positive for Ureaplasma parvum . Empirical treatment was suspended, and treatment with intravenous azithromycin was initiated (12 mg once daily). Endocervical and placental exudates were also positive for U. parvum . Fifty-two days after birth, the newborn was discharged. Conclusions: The relationship between Ureaplasma spp. colonization and perinatal disease seem to be clear. However, the high frequency of vaginal Ureaplasma spp . colonization and high rates of term labor among pregnant women with this colonization make further studies necessary. Competing Interests: Competing interests: Authors state no conflict of interest. (© 2023 the author(s), published by De Gruyter, Berlin/Boston.) |
| Databáze: | MEDLINE |
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