Chronic Kidney Disease of Non-traditional Etiology in a Young Man From Central America: Geography, Poverty, and Uncertain Pathophysiology Create a Formidable Medical Challenge.
| Autor: | Milki AA; Department of Medicine, George Washington University School of Medicine and Health Sciences, Washington, USA., Bechara M; Department of Medicine, Division of Hospital Medicine, Virginia Hospital Center, Arlington, USA., Lew SQ; Department of Medicine, Division of Kidney Disease and Hypertension, George Washington University School of Medicine and Health Sciences, Washington, USA., Poon AN; Department of Medicine, Division of Hospital Medicine, George Washington University School of Medicine and Health Sciences, Washington, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 May 11; Vol. 15 (5), pp. e38876. Date of Electronic Publication: 2023 May 11 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.38876 |
| Abstrakt: | A man in his early 20s with kidney biopsy-confirmed focal segmental glomerulosclerosis (FSGS) was admitted with one month of nausea and vomiting, intermittent episodes of confusion, shortness of breath, and dysuria. He reported that many people from his native village in Central America, where he harvested sugarcane as a child, have died from kidney disease, including his father and cousin. He believed the source of disease to be agrochemicals found in the village's water supply. Although FSGS would be a rare manifestation, the patient's risk factors strongly suggested chronic kidney disease of unknown etiology (CKDu) - also known as Mesoamerican nephropathy (MeN) - a phenomenon he had never previously heard of. He took lisinopril for the last six years to manage his kidney disease. Due to uremic symptoms and abnormal electrolytes, he was initiated on hemodialysis. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Milki et al.) |
| Databáze: | MEDLINE |
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