Fetal-type posterior cerebral artery and association of rupture in posterior communicating artery aneurysms: A systematic review and meta-analysis.

Autor: Arrambide-Garza FJ; Universidad Autónoma de Nuevo León, School of Medicine, Human Anatomy Department, Mexico. Electronic address: arrambidefrancisco@hotmail.com., Alvarez-Lozada LA; Universidad Autónoma de Nuevo León, School of Medicine, Human Anatomy Department, Mexico. Electronic address: luis.adrian.1a@gmail.com., de León-Gutiérrez H; Universidad Autónoma de Nuevo León, School of Medicine, Plataforma INVEST Medicina UANL-KER Unit Mayo Clinic, KER Unit, México, Mexico. Electronic address: humberto.dleong@gmail.com., Villarreal-Silva EE; Universidad Autónoma de Nuevo León, School of Medicine, Neurosurgery Department, Mexico. Electronic address: eliud.villarrealsl@uanl.mx., Alvarez-Villalobos NA; Universidad Autónoma de Nuevo León, School of Medicine, Plataforma INVEST Medicina UANL-KER Unit Mayo Clinic, KER Unit, México, Mexico; Knowledge and Evaluation Research Unit, Mayo Clinic, United States. Electronic address: neri_alex@hotmail.com., Quiroga-Garza A; Universidad Autónoma de Nuevo León, School of Medicine, Human Anatomy Department, Mexico; Instituto Mexicano del Seguro Social, Delegación Nuevo Leon, Monterrey, Mexico. Electronic address: dr.aquirogag@gmail.com., Elizondo-Omaña RE; Universidad Autónoma de Nuevo León, School of Medicine, Human Anatomy Department, Mexico. Electronic address: rod_omana@yahoo.com., Guzman-Lopez S; Universidad Autónoma de Nuevo León, School of Medicine, Human Anatomy Department, Mexico. Electronic address: dr.santos.anato@gmail.com.
Jazyk: angličtina
Zdroj: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2023 Aug; Vol. 231, pp. 107815. Date of Electronic Publication: 2023 Jun 05.
DOI: 10.1016/j.clineuro.2023.107815
Abstrakt: Background: The morbidity and mortality of intracranial aneurysm rupture motivate the risk evaluation of the patient´s characteristics and aneurysm's morphology. Brain vessel variants lead to hemodynamic changes that could increase risk. This study aims to evaluate the fetal posterior cerebral artery (fPCA) as a risk factor for the formation, rupture, and recurrence of the posterior communicating artery (PComA) aneurysm.
Methods: A search strategy was performed in MEDLINE, Scopus, Web of Science, and EMBASE databases for studies that evaluated the risk of appearance, rupture, and recurrence of PComA aneurysms with the presence of fPCA. Newcastle-Ottawa Scale and AXIS were used for quality assessment. The primary and secondary outcomes were evaluated and interpreted with an odds ratio (OR) and their 95% confidence intervals (CI).
Results: A total of 577 articles were reviewed. Thirteen studies were included for the qualitative analysis, and ten studies for the meta-analysis. All cohort studies were classified as poor quality, and all cross-sectional studies with moderate risk. The unadjusted OR resulted in 1.57 (n = 6, 95% CI 1.13-2.19, p = <0.001, I 2 =0%) between the presence of fPCA and PComA aneurysm rupture.
Conclusion: There is a significant association of aneurysm formation and rupture of PComA aneurysms in the presence of fPCA. This may be triggered by the hemodynamic alterations caused by the variation, leading to changes in the vessel wall.
Competing Interests: Declaration of Competing Interest The authors declare that they have no conflict of interest. The authors have no relevant financial or non-financial interests to disclose
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: