Antineuronal autoantibodies induced paraneoplasic syndrome in schizophrenia spectrum disorders: case report.

Autor: Jaballah F; Avicenna (A) Department, Razi Hospital, Tunis-El Manar University., Ben Hamed N; Avicenna (A) Department, Razi Hospital, Tunis-El Manar University., Hamzaoui S; Avicenna (A) Department, Razi Hospital, Tunis-El Manar University., Ayadi MA; Carcinoligical Surgery Department, Salah Azaiez Hospital, Tunis-El Manar University, Tunis, Tunisia., Zgueb Y; Avicenna (A) Department, Razi Hospital, Tunis-El Manar University., Jomli R; Avicenna (A) Department, Razi Hospital, Tunis-El Manar University.
Jazyk: angličtina
Zdroj: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2023 Apr 11; Vol. 85 (5), pp. 2046-2048. Date of Electronic Publication: 2023 Apr 11 (Print Publication: 2023).
DOI: 10.1097/MS9.0000000000000540
Abstrakt: Secondary psychiatric symptoms are usually suspected when there is an atypical presentation of the symptoms or a lack of response to psychotropic medication.
Case Presentation: Our case is about a woman aged 62 years old, with a history of mental disorder who presented psychiatric symptomatology after years of being stabilized by antipsychotics. She was later investigated due to a mass in her breast. Carcinoma was diagnosed, and her psychiatric symptomatology was resolved after the tumerectomy.
Discussion: The therapeutic difficulty is the major problem of psychic disorders in the context of paraneoplastic syndrome. Several literature review have suggested a relationship between schizophrenia and antineuronal antibodies in the context of paraneoplastic syndrome. Treating the tumor can solve psychiatric symptoms better than psychotic treatment.
Conclusions: The aim of our study is to highlight the importance of a complete medical evaluation to identify the psychiatric presentations of organic disorders associated with psychiatric manifestation and to ensure an early diagnosis.
Competing Interests: The authors declare that they have no financial conflict of interest with regard to the content of this report.
(Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze: MEDLINE