Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds.

Autor:	Mohammed S; The Ohio State University, College of Pharmacy, Division of Medicinal Chemistry and Pharmacognosy, Columbus, Ohio, 43210, USA., West JS; The Ohio State University, College of Pharmacy, Division of Medicinal Chemistry and Pharmacognosy, Columbus, Ohio, 43210, USA., Mitton-Fry MJ; The Ohio State University, College of Pharmacy, Division of Medicinal Chemistry and Pharmacognosy, Columbus, Ohio, 43210, USA.
Jazyk:	angličtina
Zdroj:	SynOpen (2017) [SynOpen] 2022 Jun; Vol. 6 (2), pp. 110-131. Date of Electronic Publication: 2022 Apr 14.
DOI:	10.1055/a-1826-2852
Abstrakt:	The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest. Accordingly, there is a demand for straightforward synthetic protocols toward such compounds using readily available starting materials. In the past decade, there have been substantial developments in heterocycle synthesis, especially in metal-catalyzed and iodine-assisted approaches. This graphical review focuses on notable reactions from the past decade using aryl and heteroaryl methyl ketones as starting materials, including representative reaction mechanisms. Competing Interests: Conflict of Interest The authors declare no conflict of interest.
Databáze:	MEDLINE
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