Variability in Swallowed Topical Corticosteroid Practice Patterns for Treatment of Pediatric Eosinophilic Esophagitis.

Autor: Syverson EP; From the Boston Children's Hospital, Boston, MA.; Harvard Medical School, Boston, MA., Tobin M; Stony Brook Children's Hospital, Stony Brook, NY., Patton T; University of Chicago Medicine, Chicago, IL., Franciosi JP; Nemours Children's Hospital, Orlando, FL.; University of Central Florida College of Medicine, Orlando, FL., Gupta SK; Indiana University School of Medicine/Riley Hospital for Children, Indianapolis, IN., Venkatesh RD; Nationwide Children's Hospital, Columbus, OH.; The Ohio State University, Columbus, OH.
Jazyk: angličtina
Zdroj: Journal of pediatric gastroenterology and nutrition [J Pediatr Gastroenterol Nutr] 2023 Aug 01; Vol. 77 (2), pp. 256-259. Date of Electronic Publication: 2023 May 19.
DOI: 10.1097/MPG.0000000000003834
Abstrakt: Given the variety of preparations and lack of standardization of swallowed topical corticosteroids (STC) for treatment of eosinophilic esophagitis (EoE), we sought to better understand STC prescribing practices of pediatric gastroenterologists. A 12-question survey was distributed to members of North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Eosinophilic Gastrointestinal Disease Special Interest Group and responses were analyzed. Forty-two of 68 physicians responded. Oral viscous budesonide (OVB) was overall first choice STC in 31 (74%) survey respondents, with OVB most frequently utilized in patients under 5 years old and fluticasone propionate in patients 13-18 years old. Nineteen types of mixing vehicles were used for OVB preparation, the 3 most frequent being sucralose, honey, and artificial maple syrup. Insurance coverage, cost, and patient compliance were most frequently cited barriers to STC use. Highly variable STC prescribing practices reported by this group highlights the need for standardization of STC treatment in EoE.
Competing Interests: E.P.S. has served on the medical advisory board for Sanofi/Regeneron. The remaining authors report no conflicts of interest.
(Copyright © 2023 by European Society for European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.)
Databáze: MEDLINE
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