Photobiomodulation increases uprighting tooth movement and modulates IL-1β expression during orthodontically bone remodeling.

Autor: Murakami-Malaquias-Silva F; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., Perim Rosa E; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., Malavazzi TCS; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., Silva T; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., de Santana Sarmento DJ; Universidade Estadual da Paraíba, João Pessoa, Brazil., Garcez AS; São Leopoldo Mandic, School of Dentistry, São Paulo, Brazil., Fernandes MUR; São Leopoldo Mandic, School of Dentistry, São Paulo, Brazil., Tortamano A; Department of Orthodontics, School of Dentistry, University of São Paulo, São Paulo, Brazil., Ramalho KM; School of Dentistry, Israelita Albert Einstein Fondation, São Paulo, Brazil., Motta LJ; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., Fernandes KPS; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., Bussadori SK; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., Mesquita-Ferrari RA; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil., Horliana ACRT; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil.
Jazyk: angličtina
Zdroj: Journal of biophotonics [J Biophotonics] 2023 Sep; Vol. 16 (9), pp. e202300013. Date of Electronic Publication: 2023 Jun 21.
DOI: 10.1002/jbio.202300013
Abstrakt: This study investigated the effects of photobiomodulation (PBM) in acceleration of orthodontic movement of inferior molar uprighting movement. Thirty-four individuals, with indication of molar uprighting movement for oral rehabilitation, were randomly divided in two groups: verticalization + PBM (808 nm, 100 mW, 1 J per point, 10 points and 25 J/cm 2 ) or verticalization + PBM simulation. Elastomeric chain ligatures were changed every 30 days for 3 months. FBM was performed immediately, 24 h, 72 h, 1 and 2 months after activation. The primary outcome was the amount of uprighting movement. Secondary outcomes were pain, amount of medication, OHIP-14 questionnaire, and cytokine IL-1β. PBM group increase uprighting movement when compared to control after 3 months and modulate IL-1β expression. For pain control, the amount of medication and OHIP-14 no difference were found. This study suggests that PBM accelerates tooth movement during molar uprighting, due to modulation of IL-1β during bone remodeling.
(© 2023 Wiley-VCH GmbH.)
Databáze: MEDLINE
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