Increased risk of hospitalization and death in Mexican children and adolescents with COVID-19 and comorbidities.

Autor:	Méndez-Hernández P; Facultad de Ciencias de la Salud, Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico.; Departamento de Calidad y Educación en Salud Secretaría de Salud de Tlaxcala, Tlaxcala, Mexico., Hernández-Galdamez DR; INCAP Research Center for the Prevention of Chronic Diseases, Instituto de Nutrición de Centro América y Panamá, Guatemala City, Guatemala., González-Block MA; Universidad Anáhuac, Mexico City, Mexico.; Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.; Evisys Consulting, Mexico City, Mexico., Romo-Dueñas DK; Universidad del Valle de Guatemala, Centro de Estudios en Salud, Guatemala City, Guatemala., Cahuantzi-Tamayo RM; Departamento de Calidad y Educación en Salud Secretaría de Salud de Tlaxcala, Tlaxcala, Mexico., Texis-Morales O; Departamento de Calidad y Educación en Salud Secretaría de Salud de Tlaxcala, Tlaxcala, Mexico., Medina-Urzúa JJ; Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico., Cerón-Meza R; Facultad de Agrobiología, Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico., Hernández-Vicente IA; INCAP Research Center for the Prevention of Chronic Diseases, Instituto de Nutrición de Centro América y Panamá, Guatemala City, Guatemala.; Hospital General de Huamantla, Secretaría de Salud de Tlaxcala, Tlaxcala, Mexico., Lumbreras-Guzmán M; INCAP Research Center for the Prevention of Chronic Diseases, Instituto de Nutrición de Centro América y Panamá, Guatemala City, Guatemala.; Centro de Salud Urbano de Villa Vicente Guerrero Secretaría de Salud de Tlaxcala, Tlaxcala, Mexico.
Jazyk:	angličtina
Zdroj:	Boletin medico del Hospital Infantil de Mexico [Bol Med Hosp Infant Mex] 2023; Vol. 80 (2), pp. 105-114.
DOI:	10.24875/BMHIM.22000124
Abstrakt:	Background: Although COVID-19 (coronavirus disease 2019) in children is usually mild, they need hospitalization and intensive care in exceptional cases. Adverse outcomes have been observed mainly among children with comorbidities, justifying their vaccination. This study aimed to assess the risk of hospitalization and death in Mexican children and adolescents with COVID-19 and comorbidities. Methods: A cross-sectional study was performed on 366,542 confirmed COVID-19 cases under 18 years, reported by the Mexican Ministry of Health up to July 9, 2022. Logistic regression models were performed. Results: The mean age was 10.98 years, 50.6% were male, and 7.3% reported at least one comorbidity. The percentage of hospitalization and death in COVID-19 patients with and without comorbidities was 3.52%, and 0.20%, respectively; children with comorbidities presented a higher percentage of hospitalization (14.0%) and death (1.9%). The probability of hospitalization was 5.6 times greater in pediatric patients with COVID-19 and comorbidities, and the comorbidities that showed the greatest risk were immunosuppression (odds ratio (OR) 22.06), chronic kidney disease (CKD) (11.36), and cardiovascular diseases (5.66). The probability of death in patients with comorbidities was 11.01 times higher than in those without diseases, and the highest risk was observed in those with CKD (OR 12.57), cardiovascular diseases (6.87), and diabetes (5.83). Conclusions: Pediatric patients with comorbidities presented a higher risk of severe COVID-19. It is suggested that vaccination should be promoted with greater emphasis on pediatric patients with comorbidities. (Copyright: © 2023 Permanyer.)
Databáze:	MEDLINE
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