Naturally acquired antibody response to Plasmodium falciparum and Plasmodium vivax among indigenous Orang Asli communities in Peninsular Malaysia.
Autor: | Rahim MAFA; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Munajat MB; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Dian ND; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Seri Rakna MIM; District Health Office of Gua Musang, Gua Musang, Kelantan, Malaysia., Wahid W; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Ghazali N; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Hassan NW; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Abdul Manap SNA; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Kasri MRM; District Health Office of Gua Musang, Gua Musang, Kelantan, Malaysia., Mohamed AI; District Health Office of Gua Musang, Gua Musang, Kelantan, Malaysia., Osman E; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia., Chuangchaiya S; Department of Community Health, Faculty of Public Health, Kasetsart University, Sakon Nakhon, Thailand., Lubis IND; Department of Paediatric, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia., Divis PCS; Malaria Research Centre, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia., Kaneko A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.; Department of Parasitology, Graduate School of Medicine, Osaka City University, Osaka, Japan., Tetteh KKA; Department of Infection Biology, Faculty of Infectious Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Idris ZM; Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia. |
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Jazyk: | angličtina |
Zdroj: | Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Apr 20; Vol. 13, pp. 1165634. Date of Electronic Publication: 2023 Apr 20 (Print Publication: 2023). |
DOI: | 10.3389/fcimb.2023.1165634 |
Abstrakt: | Malaria remains a public health problem in many parts of the world. In Malaysia, the significant progress towards the national elimination programme and effective disease notification on malaria has resulted in zero indigenous human malaria cases since 2018. However, the country still needs to determine the extent of malaria exposure and transmission patterns, particularly in high-risk populations. In this study, a serological method was used to measure transmission levels of Plasmodium falciparum and Plasmodium vivax among indigenous Orang Asli communities in Kelantan, Peninsular Malaysia. A community-based cross-sectional survey was conducted in three Orang Asli communities (i.e., Pos Bihai, Pos Gob, and Pos Kuala Betis) in Kelantan from June to July 2019. Antibody responses to malaria were assessed by enzyme-linked immunosorbent assay (ELISA) using two P. falciparum (PfAMA-1 and PfMSP-1 Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Rahim, Munajat, Dian, Seri Rakna, Wahid, Ghazali, Hassan, Abdul Manap, Kasri, Mohamed, Osman, Chuangchaiya, Lubis, Divis, Kaneko, Tetteh and Idris.) |
Databáze: | MEDLINE |
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